Paper Details

  1. Home
  2. Paper Details

Predictors of response to alprazolam and placebo in patients with panic disorder.

Author: BallengerJ C, LydiardR B, MihalkoD, NoyesR, SieversG, WoodmanC L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Older age and lower baseline anxiety and phobic symptoms were associated with a better response to alprazolam for panic disorder. Lower baseline anxiety and panic attacks, and a lack of previous psychiatric treatment, were associated with a better response to placebo.
Paper Details　
Original Abstract of the Article :
Date from a panic disorder treatment study with 506 patients, comparing alprazolam and placebo in a double-blind manner for 8 weeks, were analyzed to identify demographic and clinical characteristics of the patients that might predict response to treatment. The strongest predictors of response to al...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/0165-0327(94)90146-5

データ提供：米国国立医学図書館（NLM）

Unraveling the Mystery of Panic Disorder Response

Panic disorder is a debilitating condition that can significantly impact an individual's quality of life. This study dives into the complexities of panic disorder treatment, investigating the factors that predict response to alprazolam and placebo. The researchers analyzed data from a comprehensive clinical trial involving 506 patients, meticulously exploring demographic and clinical characteristics to identify potential predictors of treatment success. Their findings offer valuable insights into the individualized nature of panic disorder treatment, revealing that factors such as age and baseline anxiety levels play a crucial role in treatment outcomes.

Age Matters: Understanding Individual Differences in Panic Disorder Treatment

The study revealed that patients over 40 years of age were more likely to respond positively to alprazolam. This intriguing finding suggests that age may be a significant factor in determining the effectiveness of treatment for panic disorder. As Dr. Camel, I can relate to this finding as I have seen countless individuals, both young and old, struggle with this condition. Each individual's journey is unique, and understanding these differences is vital for creating effective treatment strategies.

Navigating the Landscape of Panic Disorder Treatment

It's important to understand the unique needs of each patient, particularly in the context of panic disorder. Recognizing the factors that predict response to treatment can help healthcare professionals tailor treatment plans to individual patients, ultimately leading to improved outcomes. This study serves as a valuable reminder that there's no one-size-fits-all approach to managing panic disorder. We must remain vigilant in our quest to understand the complex interplay of factors that influence treatment effectiveness.

Dr.Camel's Conclusion

Imagine a desert oasis, a place of peace and tranquility. Panic disorder is like a sudden sandstorm, disrupting this serenity. This study sheds light on the factors that can influence the effectiveness of treatments, helping us navigate the complexities of this condition. Understanding the unique needs of each individual, like a traveler seeking shelter in the desert, is essential for creating effective treatment strategies.

Date :
  1. Date Completed 1994-05-09
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

8151049

DOI: Digital Object Identifier

10.1016/0165-0327(94)90146-5

Related Literature

Article Analysis
・Effective treatment of panic disorder
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.