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Oral tramadol, a mu-opioid agonist and monoamine reuptake-blocker, and morphine for strong cancer-related pain.

Author: OsterwalderB, SchimkeJ, SennH J, Wilder-SmithC H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Tramadol was as effective as morphine in controlling pain in cancer patients, with a lower rate of side effects. Tramadol was associated with less nausea and constipation than morphine.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Opioid and spinal monoaminergic agonists have distinct analgesic properties, which may potentiate each other. Tramadol has both opioid and monoaminergic agonist actions. This initial study compared the analgesic and toxic effects of tramadol and morphine in patients with strong cancer pa...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8186157

データ提供：米国国立医学図書館（NLM）

Tramadol vs. Morphine: A Desert Oasis for Strong Cancer Pain

The desert of cancer pain can be a harsh and unforgiving landscape, demanding innovative approaches for effective relief. This study compared the analgesic effects of tramadol and morphine in patients experiencing strong cancer-related pain. The authors employed a double-blind, randomized, cross-over design to evaluate the efficacy and tolerability of both medications. The results revealed that tramadol achieved similar pain control to morphine, but with fewer side effects. This finding suggests that tramadol may be a valuable alternative for managing strong cancer pain, potentially offering a more comfortable experience for patients.

Tramadol: A More Tolerable Oasis for Cancer Pain

The study findings suggest that tramadol may provide a more tolerable option for managing strong cancer pain compared to morphine. This discovery, like a refreshing oasis in the desert, offers hope for patients seeking effective pain relief with fewer side effects.

Navigating the Desert of Cancer Pain: Tramadol Offers a New Path

Tramadol, like a well-charted path through the desert, may offer a more tolerable option for managing cancer pain. This research highlights the importance of considering the individual patient's needs and preferences when choosing pain relief strategies.

Dr.Camel's Conclusion

This study provides valuable insights into the comparative analgesic effects of tramadol and morphine for strong cancer pain. The findings suggest that tramadol offers a promising alternative for managing cancer pain, potentially providing a more comfortable experience for patients. However, it's crucial to consult with a healthcare professional to determine the best course of action for your individual needs.

Date :
  1. Date Completed 1994-06-22
  2. Date Revised 2020-02-03
Further Info :

Pubmed ID

8186157

DOI: Digital Object Identifier

S0923-7534(19)62973-X

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PICO Info
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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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