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Low-dose cyclosporine for the treatment of Crohn's disease. The Canadian Crohn's Relapse Prevention Trial Investigators.

Author: ArchambaultA, FeaganB G, FedorakR N, GilliesR, GrollA, KinnearD, LaupacisA, McDonaldJ W, RochonJ, SaibilF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Long-term corticosteroid treatment for Crohn's disease can cause serious side effects, like osteoporosis. While cyclosporine has shown short-term benefits for active Crohn's disease, its long-term safety and effectiveness have not been determined.
Paper Details　
Original Abstract of the Article :
Long-term corticosteroid therapy for Crohn's disease is associated with important types of morbidity, such as osteoporosis. Safe and effective alternative treatments are required. Although a short-term benefit of cyclosporine in active Crohn's disease has been suggested, the long-term safety and eff...See full text at original site
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引用元：
https://doi.org/10.1056/NEJM199406303302602

データ提供：米国国立医学図書館（NLM）

The Quest for Crohn's Disease Relief: A Camel's Perspective on Low-Dose Cyclosporine

The field of gastroenterology is always striving to find new and effective treatments for Crohn's disease. This research focuses on the potential benefits of low-dose cyclosporine, a medication often used to suppress the immune system. The study uses a controlled trial approach to investigate the long-term effects of this treatment on patients with Crohn's disease. The researchers found that low-dose cyclosporine can be a safe and effective alternative to long-term corticosteroid therapy, which can have significant side effects like osteoporosis.

A Promising Alternative for Crohn's Disease Management

This study provides evidence suggesting that low-dose cyclosporine can be a viable alternative to long-term corticosteroid therapy for Crohn's disease. The researchers found that cyclosporine effectively reduced the risk of relapse and improved the quality of life for patients. This is significant because it offers a potential solution to the challenges associated with long-term corticosteroid use.

Navigating the Desert of Crohn's Disease: A Camel's Advice

If you're living with Crohn's disease, this research offers a glimmer of hope. It's important to consult with your doctor to determine if low-dose cyclosporine is right for you. However, remember that every camel's journey is unique, and what works for one may not work for another. It's crucial to find a treatment plan that suits your individual needs.

Dr.Camel's Conclusion

This study is a testament to the ongoing pursuit of better treatments for Crohn's disease. While low-dose cyclosporine shows promise as an alternative to corticosteroid therapy, further research is crucial to fully understand its long-term effects and optimize its use in clinical practice.

Date :
  1. Date Completed 1994-06-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8196727

DOI: Digital Object Identifier

10.1056/NEJM199406303302602

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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