Paper Details 
Original Abstract of the Article :
Corneal stromal haze has been seen following photorefractive keratectomy with the 193-nanometer excimer laser. Topical antimetabolites aimed at decreasing the haze have been investigated in the rabbit model. We used the VISX 193-nanometer excimer laser to create 6.0-millimeter, -5.00-diopter ablatio...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/8196922

データ提供:米国国立医学図書館(NLM)

Fibroblast Inhibitors and Corneal Healing: A Desert of Haze

Corneal stromal haze, a cloudiness that can impair vision, is a potential complication following photorefractive keratectomy, a surgical procedure used to correct refractive errors. This research investigates the effectiveness of topical fibroblast inhibitors in reducing corneal haze in rabbits. It's like trying to clear the sand dunes after a desert storm, aiming to restore clarity and vision.

A Transient Benefit: Reducing Haze

The study found that topical agents, such as prednisolone acetate, 5-fluorouracil, and heparin, temporarily reduced corneal haze. It’s like a brief respite from a desert heatwave. While the initial reduction was statistically significant, the effect was not sustained over time, suggesting that these agents may provide only a transient benefit.

More Research Needed: A Continuing Journey

This research highlights the need for further investigation into the potential of fibroblast inhibitors in preventing corneal haze. It’s like a journey through a desert, requiring ongoing exploration and research to find more effective solutions.

Dr.Camel's Conclusion

The research explores the use of fibroblast inhibitors for reducing corneal haze after photorefractive keratectomy. While these agents offer a temporary benefit, further research is needed to develop more effective and lasting solutions for this challenging problem.

Date :
  1. Date Completed 1994-06-30
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8196922

DOI: Digital Object Identifier

8196922

Related Literature

SNS
PICO Info
in preparation
Languages

English

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