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Conservative surgery for the management of invasive and noninvasive carcinoma of the breast: NSABP trials. National Surgical Adjuvant Breast and Bowel Project.

Author: AndersonS, FisherB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study analyzed the long-term results of a 10-year follow-up of a randomized trial comparing lumpectomy with or without radiation therapy to modified radical mastectomy for stages I and II breast cancer. The study found that lumpectomy with radiation therapy was as effective as mastectomy in preventing tumor recurrence in the same breast and in overall survival. The results support the use of lumpectomy and radiation therapy as a standard treatment for invasive breast cancer and potentially for localized ductal carcinoma in situ.
Paper Details　
Original Abstract of the Article :
In 1976 the National Surgical Adjuvant Breast and Bowel Project (NSABP) initiated a randomized trial (B-06) to evaluate the worth of lumpectomy in the treatment of patients with stages I and II breast cancer. This report presents, for the first time, findings from that trial through 10 years of foll...See full text at original site
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引用元：
https://doi.org/10.1007/BF00348193

データ提供：米国国立医学図書館（NLM）

Exploring the Effectiveness of Lumpectomy and Radiation Therapy for Breast Cancer

This research examines the effectiveness of lumpectomy and radiation therapy in treating stages I and II breast cancer. The authors analyzed data from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-06 trial, comparing outcomes for patients treated with lumpectomy and radiation therapy to those who underwent modified radical mastectomy. The findings suggest that lumpectomy combined with radiation therapy is a safe and effective alternative to mastectomy in treating early-stage breast cancer.

Lumpectomy and Radiation Therapy: A Viable Option for Breast Cancer

This research provides strong evidence for the efficacy of lumpectomy and radiation therapy in treating early-stage breast cancer. The findings indicate that this approach is comparable to mastectomy in terms of disease-free survival and overall survival. This research has significantly impacted clinical practice, leading to a wider acceptance of lumpectomy as a standard treatment option.

Personalized Treatment Strategies

This research underscores the importance of individualized treatment approaches. The findings suggest that lumpectomy and radiation therapy are viable options for many patients with early-stage breast cancer. However, it's crucial to carefully consider individual factors such as tumor size, location, and patient preferences to determine the best course of treatment.

Dr. Camel's Conclusion

Imagine a vast desert landscape, where each oasis represents a different treatment option. This research is like a detailed exploration of one oasis, revealing its potential to provide life-sustaining resources for those facing breast cancer. It highlights the importance of considering all treatment options and tailoring them to the individual, offering a personalized path to recovery.

Date :
  1. Date Completed 1994-06-30
  2. Date Revised 2022-03-18
Further Info :

Pubmed ID

8197778

DOI: Digital Object Identifier

10.1007/BF00348193

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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