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Cyclosporin A retention enemas in refractory distal ulcerative colitis and 'pouchitis'.
Author: CampbellA, DaltonH R, JewellD P, MerrettM N, WinterT A
Original Abstract of the Article :
The aim of this study was to evaluate the use of cyclosporin enemas in patients with distal ulcerative colitis and 'pouchitis' resistant to all conventional medical therapy. In an trial 12 patients with distal ulcerative colitis unresponsive to treatment with topical and oral corticosteroids, 5-amin...See full text at original site
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引用元:
https://doi.org/10.3109/00365529309098276
データ提供:米国国立医学図書館(NLM)
A New Frontier in Ulcerative Colitis Treatment: Exploring the Use of Cyclosporin Enemas
Ulcerative colitis (UC), a chronic inflammatory bowel disease, can cause significant discomfort and impact a person's quality of life. This study explores a novel approach to treating refractory distal UC, examining the efficacy of cyclosporin enemas in patients who have not responded to conventional medical therapies. The study investigates the use of cyclosporin enemas as a potential treatment option for severe UC, focusing on its safety, effectiveness, and potential side effects.
A New Pathway to Relief: Evaluating Cyclosporin Enemas for Refractory Ulcerative Colitis
The study found that cyclosporin enemas were safe and potentially effective in treating refractory distal UC, demonstrating a significant improvement in symptoms for a majority of patients. The study also highlighted the correlation between clinical improvement and histologic changes, suggesting that cyclosporin enemas may effectively address both the clinical manifestations and underlying inflammation of UC. However, the study also noted that some patients did not respond to treatment, highlighting the need for careful patient selection and individualized therapy.
Exploring New Horizons: The Potential of Cyclosporin Enemas in Ulcerative Colitis Management
This study offers a promising glimpse into the potential of cyclosporin enemas as a treatment option for refractory distal UC, suggesting that this approach may offer a valuable alternative for patients who have not responded to conventional therapies. Further research is crucial to determine the long-term effectiveness of cyclosporin enemas, optimize treatment regimens, and explore its potential role in other forms of UC.
Dr.Camel's Conclusion
This study explores the use of cyclosporin enemas as a potential treatment for refractory distal ulcerative colitis (UC). The findings suggest that cyclosporin enemas may be a safe and effective option for some patients, offering a new avenue for managing severe UC. Further research is needed to fully assess the long-term benefits of this approach, refine treatment protocols, and explore its application in other forms of UC. This research represents a promising step in the ongoing effort to develop more effective and personalized treatments for inflammatory bowel diseases.
Date :
- Date Completed 1993-10-29
- Date Revised 2019-08-14
Further Info :
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