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Is magnesium content in erythrocytes suitable for evaluating cation retention after oral physiological supplementation in marginally magnesium-deficient subjects?

Author: AmbrosiniG, BargelliniA, BorellaP, ConcariM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study of healthy subjects found that oral magnesium supplementation significantly increased urinary magnesium excretion and erythrocyte magnesium levels, suggesting the existence of a saturable mechanism that prevents magnesium overload.
Paper Details　
Original Abstract of the Article :
In this study, the effects of oral magnesium supplementation were evaluated on plasma, erythrocyte, and urinary cation levels. The study was carried out with an open, cross-over and randomized design. Healthy subjects received two sachets per day of magnesium (366 mg Mg2+/d) for two 28 d cycles, sep...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8274360

データ提供：米国国立医学図書館（NLM）

Magnesium: A Vital Nutrient for Health

Magnesium is an essential mineral that plays a crucial role in numerous bodily functions, from muscle contraction to nerve impulse transmission. This study explores the effectiveness of oral magnesium supplementation in individuals with marginal magnesium deficiency. The researchers analyzed the impact of magnesium supplementation on plasma, erythrocyte, and urinary levels of magnesium, providing valuable insights into the body's response to magnesium intake.

Erythrocytes: A Window into Magnesium Status

The study revealed that while plasma magnesium levels showed only modest increases with supplementation, erythrocyte magnesium levels exhibited a significant and sustained elevation. This suggests that erythrocytes, the red blood cells, may serve as a more reliable indicator of magnesium status than plasma levels. This finding is particularly important for assessing the effectiveness of magnesium supplementation and ensuring adequate levels of this essential mineral.

Maintaining Magnesium Balance: Essential for Health

Magnesium plays a vital role in maintaining overall health, and deficiency can lead to a range of problems. This study underscores the importance of monitoring magnesium levels, particularly in individuals who may be at risk for deficiency. While oral supplementation can be effective, individual needs may vary, and it's essential to consult with a healthcare professional to determine the appropriate dose and duration of supplementation.

Dr.Camel's Conclusion

Just as a camel thrives in the desert thanks to its ability to store water, our bodies require magnesium for optimal function. This research shines a light on the importance of monitoring magnesium levels and highlights the potential of erythrocytes as a reliable indicator of magnesium status. It's a reminder that even in the seemingly vast and arid desert of our bodies, essential nutrients like magnesium play a vital role in maintaining our health and well-being.

Date :
  1. Date Completed 1994-02-04
  2. Date Revised 2016-03-21
Further Info :

Pubmed ID

8274360

DOI: Digital Object Identifier

8274360

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Languages

English

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