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Six months versus nine months chemotherapy for tuberculosis of lymph nodes: final results.

Author: CampbellI A, FriendJ A, JenkinsP A, OrmerodL P, PrescottR J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study of 157 patients with peripheral lymph node tuberculosis found that a 6-month Z2H6R6 regimen was as effective as 9-month regimens Z2H9R9 and E2H9R9 in patients with fully sensitive organisms.
Paper Details　
Original Abstract of the Article :
Of 199 patients treated for peripheral lymph node tuberculosis, 157 completed treatment as planned. Fifty received E2H9R9, 56 Z2 H9R9 and 51 Z2H6R6 regimens (E = Ethambutol; H = Isoniazid; R = Rifampicin; Z = pyrazinamide: numbers denote duration of therapy in months). In follow-up from 9 to 30 mont...See full text at original site
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引用元：
https://doi.org/10.1016/s0954-6111(05)80265-3

データ提供：米国国立医学図書館（NLM）

Tuberculosis of Lymph Nodes: A Shorter Treatment Regimen

The treatment of tuberculosis (TB) is a complex and lengthy process. This study investigates the effectiveness of a shorter six-month chemotherapy regimen compared to longer nine-month regimens for patients with peripheral lymph node TB. The researchers compared three different regimens in 157 patients, analyzing the outcomes in terms of disease recurrence and overall effectiveness. The study found no significant differences between the six-month regimen and the nine-month regimens in terms of disease recurrence or the need for additional treatment.

A New Path: Optimizing TB Treatment Duration

This research provides compelling evidence for the effectiveness of a shorter six-month chemotherapy regimen for patients with fully sensitive peripheral lymph node TB. This shorter regimen offers potential benefits in terms of patient convenience, adherence, and cost reduction.

Managing TB: A Collaborative Effort

The treatment of TB requires a collaborative effort between healthcare providers and patients. This study underscores the importance of carefully selecting the most appropriate regimen for each patient, considering factors such as disease severity, drug sensitivity, and patient adherence.

Dr.Camel's Conclusion

Imagine a camel traversing a desert, carrying a precious cargo of medicine. This study explores whether a shorter journey is possible without compromising the effectiveness of treatment for tuberculosis of lymph nodes. The research suggests that a shorter path can be just as effective.

Date :
  1. Date Completed 1994-02-22
  2. Date Revised 2019-09-04
Further Info :

Pubmed ID

8290746

DOI: Digital Object Identifier

10.1016/s0954-6111(05)80265-3

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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