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Treatment of infantile spasms with high-dosage vitamin B6.

Author: BenningerC, MittermaierG, PietzJ, RatingD, SchäferH, SontheimerD

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

High-dose vitamin B6 is effective in treating recently manifested infantile spasms in some children, but further studies are needed to confirm efficacy.
Paper Details　
Original Abstract of the Article :
High-dose vitamin B6 (pyridoxine-HCl, 300 mg/kg/day orally) was introduced as the initial treatment of recently manifested infantile spasms in 17 children (13 symptomatic cases with identified brain lesion and 4 cryptogenic cases). 5 of 17 children (2 cryptogenic, 2 with severe pre/perinatal brain d...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1111/j.1528-1157.1993.tb00458.x

データ提供：米国国立医学図書館（NLM）

High-Dosage Vitamin B6: A Potential Treatment for Infantile Spasms

Infantile spasms, a severe form of epilepsy characterized by sudden, brief seizures, can have a significant impact on infant development. This study investigates the effectiveness of high-dosage vitamin B6 as a potential treatment for infantile spasms. Researchers treated 17 children with recently manifested infantile spasms, 13 of whom had symptomatic cases with identified brain lesions and 4 with cryptogenic cases.

High-Dosage Vitamin B6: A Potential Treatment Option for Some Infants

The study found that 5 out of 17 children, including 2 with cryptogenic cases and 3 with severe pre/perinatal brain damage or Sturge-Weber syndrome, responded favorably to high-dosage vitamin B6. All five responders experienced seizure freedom within the first 4 weeks of treatment, with no relapse of infantile spasms.

A Beacon of Hope for Infants with Infantile Spasms

Think of infantile spasms as a desert storm, threatening to disrupt the fragile development of an infant. High-dosage vitamin B6, like a beacon of hope, offers a potential avenue for treatment, providing relief from seizures and promoting normal development.

Dr. Camel's Conclusion

This study provides preliminary evidence for the potential effectiveness of high-dosage vitamin B6 in a small subset of infants with infantile spasms. However, it is essential to conduct controlled clinical trials to further evaluate the efficacy and safety of this treatment approach.

Date :
  1. Date Completed 1993-08-17
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

8330589

DOI: Digital Object Identifier

10.1111/j.1528-1157.1993.tb00458.x

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Languages

English

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