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Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group.

Author: CutlerJ A, ElmerP J, FlackJ M, GranditsG A, GrimmR H, McDonaldR, NeatonJ D, PrineasR J, SchoenbergerJ A, StamlerJ

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

This randomized, double-blind, placebo-controlled clinical trial found that drug treatment in combination with nutritional-hygienic intervention was more effective in preventing cardiovascular and other clinical events than was nutritional-hygienic treatment alone. The study involved 837 hypertensive men and women, aged 45 to 69 years, with diastolic blood pressure less than 100 mm Hg.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To compare six antihypertensive interventions for the treatment of mild hypertension. DESIGN: Randomized, double-blind, placebo-controlled clinical trial. SETTING: Four hypertension screening and treatment centers in the United States. PARTICIPANTS: Hypertensive men and women, aged 45 ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8336373

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Hypertension: Exploring Different Treatment Strategies

The desert of hypertension research continues to be a complex and ever-evolving landscape, with ongoing efforts to develop safe and effective treatment strategies. This research investigates the effectiveness of six antihypertensive interventions, comparing them to placebo in a randomized, double-blind, placebo-controlled clinical trial. The authors followed a cohort of hypertensive individuals for an average of 4.4 years, evaluating blood pressure, quality of life, side effects, and cardiovascular outcomes.

A Glimpse into the Desert of Hypertension: Uncovering the Benefits of Drug Treatment

The study finds that drug treatment, in combination with nutritional-hygienic intervention, is significantly more effective in reducing blood pressure and preventing cardiovascular events compared to nutritional-hygienic treatment alone. This finding suggests that drug therapy plays a crucial role in managing hypertension, offering a valuable tool for improving patient outcomes. The authors also observe that the different drug treatments had minimal differences in terms of efficacy, suggesting that there may be several effective options available for patients.

Navigating the Desert of Hypertension: Finding the Right Treatment Strategy

This research underscores the importance of considering both drug therapy and lifestyle modifications in managing hypertension. The study's findings highlight the potential benefits of drug treatment, while emphasizing the need for personalized treatment plans that consider individual patient needs and preferences. The study also underscores the importance of ongoing research to develop new and improved antihypertensive treatments, potentially leading to better outcomes for patients with hypertension.

Dr. Camel's Conclusion

This research offers valuable insights into the effectiveness of different treatment strategies for hypertension, highlighting the potential benefits of drug therapy in combination with lifestyle modifications. The study underscores the importance of a personalized approach to hypertension management, taking into account individual patient needs and preferences.

Date :
  1. Date Completed 1993-08-23
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

8336373

DOI: Digital Object Identifier

8336373

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