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Cisplatin-cyclophosphamide-mitomycin combination chemotherapy with supportive care versus supportive care alone for treatment of metastatic non-small-cell lung cancer.
Author: CantoneA, CarteiF, CarteiG, CausaranoD, GencoG, GiraldiT, InterlandiG, TobaldinA
Original Abstract of the Article :
Patients with TNM stage IV non-small-cell lung cancer have short survival times. Previous controlled studies comparing chemotherapy and supportive care for the treatment of this type of cancer have not given consistent results, have included patients with different disease stages, and have rarely re...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1093/jnci/85.10.794
データ提供:米国国立医学図書館(NLM)
Chemotherapy vs. Supportive Care: A Battle in the Desert of Non-Small-Cell Lung Cancer
The desert of non-small-cell lung cancer (NSCLC) is a harsh and unforgiving place, with limited options for those who find themselves lost in its vastness. This study delves into the battle against metastatic NSCLC, comparing the effects of chemotherapy (cisplatin, cyclophosphamide, and mitomycin) with supportive care alone. Previous studies have yielded inconsistent results, often plagued by variability in patient populations and inconsistent drug dosages. This research aimed to shed light on this challenging landscape, providing a more comprehensive understanding of the effectiveness of chemotherapy in advanced NSCLC.
Navigating the Desert: Chemotherapy's Role in Advanced NSCLC
The authors acknowledge the harsh realities of metastatic NSCLC, emphasizing the short survival times for these patients. They meticulously compared the outcomes of chemotherapy with supportive care alone, considering factors such as disease stage and drug dosage intensity. The findings of this research, while not conclusive, suggest that chemotherapy may offer some benefits in managing advanced NSCLC, but further research is crucial to solidify its role. The authors also highlighted the need for consistent drug dosage and patient selection to improve treatment efficacy.
A Journey Through the Desert: Hope and Challenges in NSCLC
The journey through the desert of NSCLC is fraught with challenges. This research reminds us that the search for effective treatments for advanced NSCLC is ongoing. We must continue to explore new therapies, refine existing ones, and personalize treatment strategies to maximize benefit for each patient. While chemotherapy may offer a path through the desert, it's crucial to acknowledge its potential side effects and to individualize treatment approaches based on each patient's unique needs.
Dr. Camel's Conclusion
The fight against metastatic NSCLC is a challenging journey through a desolate landscape. This study offers valuable insights into the role of chemotherapy, highlighting the need for consistent drug dosage and careful patient selection to maximize its effectiveness. However, the desert of NSCLC demands continued exploration, with a focus on personalized therapies and innovative treatments that offer hope to those navigating its harsh terrain.
Date :
- Date Completed 1993-06-10
- Date Revised 2019-05-12
Further Info :
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