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A double-blind study of topically applied 5% amlexanox in the treatment of aphthous ulcers.

Author: GreerR O, JuarezT, KhandwalaA, LindenmuthJ E

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Amlexanox is a drug that is used to treat aphthous ulcers, a type of mouth sore. This study found that amlexanox was effective at reducing pain, redness, and size of aphthous ulcers. No side effects were reported.
Paper Details　
Original Abstract of the Article :
A double-blind trial of amlexanox (C16H14N2O4) was carried out in 32 patients with recurrent oral aphthous ulcerations. During the treatment period, which lasted for 3 days, patients received either placebo topical paste or 5% amlexanox paste. The paste was applied by the investigator twice per day ...See full text at original site
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引用元：
https://doi.org/10.1016/s0278-2391(10)80164-8

データ提供：米国国立医学図書館（NLM）

Amlexanox: A Cool Oasis in the Desert of Aphthous Ulcers

Aphthous ulcers, those painful sores that appear in the mouth, are like a desert wind, harsh and uncomfortable. This double-blind study explores the effectiveness of amlexanox, a topical medication, in alleviating the symptoms of these troublesome ulcers. The researchers compared the effects of a 5% amlexanox paste to a placebo paste in 32 patients with recurrent aphthous ulcers. This is like comparing the effects of a refreshing oasis to a dry desert wind, observing the difference in relief. They found that amlexanox significantly reduced erythema (redness), pain, and ulcer size compared to the placebo. It's like discovering a natural remedy that can soothe the pain and accelerate healing.

Amlexanox: A Powerful Tool for Aphthous Ulcer Relief

This study provides compelling evidence for the effectiveness of amlexanox in treating aphthous ulcers. The researchers observed a significant reduction in pain, erythema, and ulcer size in the patients treated with amlexanox. This is a significant finding, as aphthous ulcers can be a source of significant discomfort and disruption to daily life. This study offers a potential solution for those suffering from these ulcers.

Finding Relief in the Desert of Oral Pain

This study highlights the importance of seeking appropriate treatment for aphthous ulcers. It's like finding a cool oasis in the desert of oral pain. While amlexanox shows promise, it is essential to consult with a healthcare professional for an accurate diagnosis and personalized treatment plan. Remember, just as we prepare for a desert journey, we must also prepare for the challenges of oral health.

Dr.Camel's Conclusion

This study demonstrates the potential of amlexanox as a safe and effective treatment for aphthous ulcers. It's like discovering a hidden oasis in the desert of oral pain, offering a source of relief and healing. While more research is always needed, this study provides hope for those suffering from these painful ulcers.

Date :
  1. Date Completed 1993-04-05
  2. Date Revised 2019-08-14
Further Info :

Pubmed ID

8445464

DOI: Digital Object Identifier

10.1016/s0278-2391(10)80164-8

Related Literature

Article Analysis
・Side Effects of amlexanox
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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