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Evaluation of cefixime in the treatment of bacterial maxillary sinusitis.

Author: EdelsteinD R, KimmelmanC P, KohlbrennerV M, KohutR I, MarinaccioA T, MatthewsB L, McCaffreyT V, ParnesS M, RappM, RybakL P

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Cefixime, an oral third-generation cephalosporin, was effective in treating bacterial sinus infections in 118 adult patients. It was well tolerated, with the most common side effect being diarrhea.
Paper Details　
Original Abstract of the Article :
The efficacy and safety of cefixime, the first oral third-generation cephalosporin, were evaluated in a multicenter clinical trial involving 118 adult patients with acute sinusitis or acute exacerbations of chronic sinusitis. Patients received a single daily dose of 400 mg of cefixime for a mean dur...See full text at original site
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引用元：
https://doi.org/10.1097/00007611-199303000-00016

データ提供：米国国立医学図書館（NLM）

Cefixime: A Promising Treatment for Bacterial Maxillary Sinusitis

Bacterial maxillary sinusitis, an infection of the sinuses that can cause pain, pressure, and congestion, is a common ailment. This multicenter clinical trial, like a desert expedition meticulously documenting the effectiveness of a newly discovered medicinal plant, evaluates the efficacy and safety of cefixime, a third-generation cephalosporin antibiotic, in treating bacterial maxillary sinusitis.

Cefixime Demonstrates Effectiveness

The researchers found that cefixime was effective in treating bacterial maxillary sinusitis, achieving clinical cure or improvement in 90% of patients. This discovery, much like a desert nomad discovering a potent healing herb, highlights the potential of cefixime as a valuable treatment option. The drug was also well tolerated, with gastrointestinal side effects being the most common.

A Valuable Tool for Treating Sinusitis

This study provides strong evidence for the effectiveness of cefixime in treating bacterial maxillary sinusitis. It offers a safe and well-tolerated alternative for patients seeking relief from this common infection. Just as a desert nomad carefully selects their tools and provisions for survival, healthcare providers now have a valuable tool to treat bacterial maxillary sinusitis.

Dr. Camel's Conclusion

This study showcases the effectiveness of cefixime in treating bacterial maxillary sinusitis. This discovery, like finding a refreshing spring in the heart of a desert, provides a much-needed solution for those battling this common ailment. As we continue to explore the world of antibiotics and their applications, we may discover even more potent and effective treatments for a range of infections.
Date :
  1. Date Completed 1993-04-15
  2. Date Revised 2019-07-02
Further Info :

Pubmed ID

8451674

DOI: Digital Object Identifier

10.1097/00007611-199303000-00016

Related Literature

Article Analysis
・Side Effects of cefixime
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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