The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia.

Author: DujovneC A, FeldmanE B, HarrisW S, HeldJ, HunninghakeD B, LaskarzewskiP M, MillerV T, QuiterE, SteinE A, TobertJ A

Paper Details 
Original Abstract of the Article :
BACKGROUND: A diet low in saturated fat and cholesterol is the standard initial treatment for hypercholesterolemia. However, little quantitative information is available about the efficacy of dietary therapy in clinical practice or about the combined effects of diet and drug therapy. METHODS: One h...See full text at original site
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引用元:
https://doi.org/10.1056/NEJM199304293281701

データ提供:米国国立医学図書館(NLM)

The Efficacy of Intensive Dietary Therapy Alone or Combined with Lovastatin in Outpatients with Hypercholesterolemia

As a researcher in the field of cardiology, I'm always seeking ways to improve the management of hypercholesterolemia, a condition that significantly increases the risk of cardiovascular disease. This study examines the efficacy of intensive dietary therapy alone or combined with lovastatin, a cholesterol-lowering drug, in outpatients with moderate hypercholesterolemia. The authors found that both dietary therapy and lovastatin had independent and additive effects on lowering LDL cholesterol levels. However, the dietary intervention alone resulted in a relatively small reduction, highlighting the importance of combining dietary modifications with medication for optimal cholesterol management.

A Balancing Act in the Desert of Cholesterol Management

This study provides valuable insights into the interplay between dietary therapy and medication in managing hypercholesterolemia. The authors demonstrate that while dietary interventions can contribute to lowering cholesterol levels, they may not be sufficient on their own. The study highlights the importance of combining dietary modifications with medication, like lovastatin, to achieve significant and sustainable reductions in LDL cholesterol levels. This finding underscores the need for a balanced approach to cholesterol management, combining lifestyle modifications with appropriate medical interventions.

Navigating the Sands of Heart Health

This research highlights the importance of a multifaceted approach to managing hypercholesterolemia, a key factor in cardiovascular health. The authors demonstrate that while dietary modifications can contribute to lowering cholesterol levels, they may not be sufficient on their own. This study reinforces the need for a comprehensive strategy that incorporates both dietary changes and appropriate medication to achieve optimal cholesterol management and reduce the risk of cardiovascular disease.

Dr. Camel's Conclusion

This study provides valuable insights into the importance of combining dietary modifications with medication, like lovastatin, to effectively manage hypercholesterolemia. The findings suggest that a multifaceted approach, incorporating both lifestyle changes and medical interventions, is crucial for achieving optimal cholesterol management and reducing the risk of cardiovascular disease.

Date :
  1. Date Completed 1993-05-04
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

8464431

DOI: Digital Object Identifier

10.1056/NEJM199304293281701

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PICO Info
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Languages

English

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