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Differential effects of triazolam and ethanol on awareness, memory, and psychomotor performance.

Author: BennettR H, CherekD R, CowanK A, RoacheJ D, SchenklerJ C

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Triazolam and ethanol produced comparable degrees of impairment on psychomotor tasks, but triazolam had a greater effect on memory.
Paper Details　
Original Abstract of the Article :
Eight normal, healthy, male volunteers each received four triazolam doses (0, 2, 4, and 8 micrograms/kg) and four ethanol doses (0, 0.25, 0.5 and 1.0 g/kg) in a double-blind, double-dummy experiment in which within-subject dose sequence was determined by a balanced Latin square design. Triazolam and...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8486815

データ提供：米国国立医学図書館（NLM）

Triazolam and Ethanol: A Comparative Study of Sedative Effects

This double-blind, double-dummy experiment investigates the effects of triazolam and ethanol on awareness, memory, and psychomotor performance. Researchers explored the relative effects of these two sedatives on cognitive and motor function, highlighting the potential differences in their impact on human behavior.

Sedative Effects: A Dance Between Triazolam and Ethanol

The study found that both triazolam and ethanol produced dose-related effects on mood, perceived drug effects, memory, and psychomotor performance. While both drugs produced comparable impairment on psychomotor tasks, triazolam was more likely to impair memory function. Think of it like two different types of desert sand – one might feel smooth and easy to navigate, while the other might be more challenging and potentially trap travelers.

Understanding Sedative Effects: Navigating the Desert of Consciousness

This research provides valuable insights into the relative effects of triazolam and ethanol on cognitive and motor function. By understanding these differences, healthcare professionals can make more informed decisions about the use of these drugs, ensuring patient safety and minimizing potential adverse effects. It's a reminder that the desert of consciousness can be navigated more effectively with a thorough understanding of the potential effects of different substances.

Dr.Camel's Conclusion

This research sheds light on the nuanced effects of triazolam and ethanol on human behavior. By comparing their impact on memory and psychomotor function, we gain a better understanding of these sedatives and their potential implications for individuals seeking relief from anxiety or insomnia. It's a reminder that the desert of consciousness can be navigated more safely and effectively with a deeper understanding of the effects of different substances.

Date :
  1. Date Completed 1993-06-10
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8486815

DOI: Digital Object Identifier

8486815

Related Literature

Article Analysis
・Effects of triazolam
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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