Multicenter, placebo-controlled study of fluoxetine in seasonal affective disorder.

Author: CorralM R, GormanC P, JoffeR T, LamR W, LevittA J, MichalonM, MorehouseR L, SteinerM, TamW, WatsonG D

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The authors investigated the efficacy and safety of fluoxetine in the treatment of winter seasonal affective disorder. METHOD: Sixty-eight outpatients who met the DSM-III-R criteria for recurrent major depressive episodes, seasonal (winter) pattern, were randomly assigned to 5 weeks of t...See full text at original site
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引用元:
https://doi.org/10.1176/ajp.152.12.1765

データ提供:米国国立医学図書館(NLM)

Multicenter, Placebo-Controlled Study of Fluoxetine in Seasonal Affective Disorder

This multicenter, placebo-controlled study investigates the efficacy and safety of fluoxetine in treating seasonal affective disorder (SAD). The study randomized 68 outpatients with SAD to receive either fluoxetine (20 mg/day) or placebo for 5 weeks. While both groups showed significant improvement, the fluoxetine group exhibited a higher clinical response rate (59%) compared to the placebo group (34%). The study suggests that fluoxetine may be an effective treatment for SAD, particularly for patients with more severe depressive symptoms.

Fluoxetine: A Potential Treatment for SAD

The study's findings provide encouraging evidence for the potential of fluoxetine as a treatment for SAD. The study's results suggest that fluoxetine may be an effective treatment option, particularly for individuals experiencing more severe depressive symptoms. This research is like a ray of sunshine breaking through the clouds of SAD, offering hope for individuals struggling with this condition.

Navigating the Desert of SAD

The study's findings offer valuable information for individuals struggling with SAD. The research suggests that fluoxetine could be an effective treatment option, potentially providing relief from the debilitating symptoms of this seasonal disorder. It's like finding a cool spring in the midst of a dry and barren desert, offering a much-needed respite from the challenges of SAD.

Dr.Camel's Conclusion

The study provides evidence for the potential efficacy of fluoxetine in treating SAD, particularly for individuals with more severe depressive symptoms. The findings highlight the importance of individualized treatment approaches and the need for further research to definitively establish fluoxetine's efficacy in this population.

Date :
  1. Date Completed 1996-01-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8526243

DOI: Digital Object Identifier

10.1176/ajp.152.12.1765

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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