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Chronomodulated 5-day infusion of floxuridine and L-folinic acid in patients with advanced malignancies: a feasibility and tolerability study.
Author: AschelterA, GarufiC, GiuntaS, LéviF, NisticòC, PaceR, TerzoliE
Original Abstract of the Article :
The best schedule for administering floxuridine (FUDR) has not yet been established. Duration of infusion, need (and dosage) of leucovorin (folinic acid, FA), and circadian timing need to be further specified. Nevertheless, FUDR delivery according to circadian rhythms has allowed increase of dose in...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/8528973
データ提供:米国国立医学図書館(NLM)
Chronomodulated 5-Day Infusion of Floxuridine and L-folinic Acid in Patients with Advanced Malignancies
The fight against cancer is a long and arduous journey, much like traversing a vast desert landscape. This research investigates a chronomodulated 5-day infusion of floxuridine (FUDR) and L-folinic acid in patients with advanced malignancies. The researchers carefully analyze the feasibility and tolerability of this treatment regimen, much like meticulously planning a caravan's route to ensure its survival in the harsh desert environment.
The study found that the 5-day chronomodulated schedule allowed for a higher dose of FUDR to be administered without increasing the incidence of severe side effects. This is like discovering a new oasis in the desert, offering a more efficient and less arduous pathway for delivering treatment. The authors recommend further investigation into the efficacy of this regimen, highlighting the importance of ongoing research in the fight against cancer.
A New Approach to Cancer Treatment
This study explores a promising new approach to cancer treatment, utilizing a chronomodulated schedule for administering chemotherapy drugs. The findings suggest that this method may enhance the effectiveness of treatment while minimizing side effects. It's like finding a hidden oasis in the desert, offering a more sustainable and less taxing way to navigate the challenges of cancer treatment.
Health Implications and Lifestyle Applications
This study emphasizes the importance of research and development in finding new and improved cancer treatments. It highlights the potential of innovative approaches like chronomodulated chemotherapy to enhance treatment efficacy and improve the lives of cancer patients. It's like discovering a new and more efficient route across a desert landscape, leading to a more effective and less arduous journey for cancer patients.
Dr.Camel's Conclusion
This research is a testament to the ongoing search for better cancer treatments. It offers a glimmer of hope for patients facing this challenging disease. It's like uncovering a hidden oasis in the vast desert of medical research, providing a new pathway towards more effective and less debilitating treatments.
Date :
- Date Completed 1996-02-01
- Date Revised 2022-03-30
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