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Randomised trial of excimer laser angioplasty versus balloon angioplasty for treatment of obstructive coronary artery disease.

Author: AppelmanY E, DavidG K, KoelemayM J, KoolenJ J, MargolisJ R, Montauban van SwijndregtE W, PiekJ J, SerruysP W, StrikwerdaS, TijssenJ G, de FeyterP J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Excimer laser angioplasty followed by balloon angioplasty provides no benefit additional to balloon angioplasty alone with respect to the initial and long-term clinical and angiographic outcome in the treatment of obstructive coronary artery disease.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Excimer laser coronary angioplasty is reported to give excellent procedural results for treatment of complex coronary lesions, but this method has not been compared with balloon angioplasty in a randomised trial. METHODS: Patients (n = 308) with stable angina and coronary lesions longer...See full text at original site
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引用元：
https://doi.org/10.1016/s0140-6736(96)90209-3

データ提供：米国国立医学図書館（NLM）

Laser vs. Balloon Angioplasty: Which Wins in Coronary Artery Disease?

Coronary artery disease (CAD) is a serious condition that affects the heart's blood supply. Excimer laser angioplasty is a technique used to open blocked coronary arteries, but its effectiveness compared to traditional balloon angioplasty has been a subject of debate. This randomized trial aimed to compare the two methods in patients with stable angina and complex coronary lesions.

A Head-to-Head Comparison of Angioplasty Techniques

The study found no significant difference between the two methods in terms of initial and long-term clinical and angiographic outcomes. Both laser angioplasty followed by balloon angioplasty and balloon angioplasty alone resulted in similar rates of death, myocardial infarction, coronary bypass surgery, and repeat angioplasty. The restenosis rate (re-narrowing of the artery) was also comparable between the two groups.

Navigating the Treatment Landscape for CAD

As a medical professional, I find this study's results intriguing. It demonstrates that for patients with stable angina and complex coronary lesions, balloon angioplasty remains a viable and effective treatment option. This study is like a signpost in the desert, guiding us towards a more informed understanding of the treatment options available for CAD. However, it's important to remember that this study focused on a specific patient population, and further research is needed to determine the best treatment approach for other patient groups with different types of coronary lesions.

Dr.Camel's Conclusion

This study is a reminder that research is a constant process of exploration and refinement. It helps us to better understand the effectiveness of different treatment approaches for CAD. While balloon angioplasty remains a viable option, ongoing research is crucial for optimizing treatment strategies and improving patient outcomes.

Date :
  1. Date Completed 1996-02-08
  2. Date Revised 2019-06-11
Further Info :

Pubmed ID

8538345

DOI: Digital Object Identifier

10.1016/s0140-6736(96)90209-3

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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