Paper Details

  1. Home
  2. Paper Details

Thrombolytic therapy compared with mechanical recanalization in non-acute peripheral arterial occlusions: a randomized trial.

Author: BounameauxH, DidierD, MeyerovitzM F, Soulier-ParmeggianiL, VogelJ J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

A short course of thrombolytic therapy prior to angioplasty improved the 1-year patency rate for claudication due to iliac or femoropopliteal occlusions. However, patients with limb-threatening ischemia had a high prevalence of peripheral embolization and dismal patency rates with this form of therapy.
Paper Details　
Original Abstract of the Article :
PURPOSE: To evaluate whether thrombolytic therapy followed by angioplasty has any added benefit compared with angioplasty alone for the treatment of chronic peripheral arterial occlusions. PATIENTS AND METHODS: Twenty patients with claudication or limb-threatening ischemia of at least 3 weeks durat...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/s1051-0443(95)71184-8

データ提供：米国国立医学図書館（NLM）

Recanalization for Peripheral Arterial Occlusions: Thrombolysis vs. Angioplasty

Peripheral arterial occlusions are a common condition that can lead to claudication (leg pain during exercise) or limb-threatening ischemia. This research, published in Journal of Vascular Surgery, investigated the effectiveness of thrombolytic therapy followed by angioplasty compared to angioplasty alone for treating chronic peripheral arterial occlusions. The study found that thrombolytic therapy followed by angioplasty resulted in a significantly improved patency rate for patients with claudication, while patients with limb-threatening ischemia had a higher risk of peripheral embolization and a lower patency rate.

Mapping the Terrain of Peripheral Arterial Occlusions: A Complex Path

This research sheds light on the complex nature of peripheral arterial occlusions, highlighting the need for tailored treatment approaches based on the severity of the condition. The authors emphasize the importance of considering both the potential benefits and risks of different treatment options.

Finding the Right Path: Navigating Peripheral Arterial Occlusions

This study provides valuable insights into the treatment of peripheral arterial occlusions, emphasizing the need for careful assessment and personalized treatment plans. Patients with peripheral arterial occlusions should consult with a vascular surgeon to determine the best treatment option for them, ensuring that they have access to the information needed to make informed decisions about their care.

Dr. Camel's Conclusion

Treating peripheral arterial occlusions can feel like navigating a treacherous desert, with multiple paths leading to different outcomes. This research helps us understand the complexities of this condition and provides valuable insights into the choices available to patients. Working closely with a healthcare professional is crucial for finding the right path and achieving the best possible outcome.
Date :
  1. Date Completed 1996-02-13
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

8541683

DOI: Digital Object Identifier

10.1016/s1051-0443(95)71184-8

Related Literature

Article Analysis
・Effective treatment of angioplasty
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.