The effect of the timing and the administration of acarbose on postprandial hyperglycaemia.

Author: HofmannU, KönigP, NitzscheG, RosakC

Paper Details 
Original Abstract of the Article :
To clarify the optimum timing for ingestion of acarbose, a 100 mg dose of this oral hypoglycaemic agent was administered 30 min before, at the beginning, and 15 min after ingestion of a test meal, and the effects of the drug on blood glucose rises were compared with increases observed after a contro...See full text at original site
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引用元:
https://doi.org/10.1111/j.1464-5491.1995.tb00409.x

データ提供:米国国立医学図書館(NLM)

Timing is Everything: Optimizing Acarbose for Postprandial Hyperglycemia

The management of [postprandial hyperglycemia] in [Type 2 diabetes] is like navigating a shifting sand dune, requiring careful attention to the timing of interventions. This research explores the impact of [acarbose], a [oral hypoglycemic agent], on [blood glucose levels] when taken at different times relative to [meal consumption]. The researchers carefully measured the effects of [acarbose] on [blood glucose, insulin, and C-peptide levels] after [test meals], similar to a meticulous desert explorer charting the changes in the landscape.

The Sweet Spot for Acarbose: Timing Matters

The study found that [acarbose] had the most significant impact on [blood glucose levels] when taken [at the beginning or 15 minutes after starting the meal]. This timing is crucial for effective management of [postprandial hyperglycemia], as it allows [acarbose] to work optimally with the body's natural [glucose regulation] mechanisms. The findings suggest that [acarbose] is most effective when used strategically, much like a desert explorer navigating the terrain to reach a valuable oasis.

Implications for Diabetes Management: Taking Acarbose with the First Bite

The study emphasizes the importance of [proper timing] for taking [acarbose]. Patients should be advised to take [acarbose] with their [first mouthful of food] to maximize its effectiveness in controlling [postprandial hyperglycemia]. This simple change in routine could significantly impact the journey of managing [diabetes] and help individuals navigate the desert of [blood sugar fluctuations] with greater ease.

Dr. Camel's Conclusion

This study highlights the critical role of [timing] in the management of [postprandial hyperglycemia]. By taking [acarbose] with the [first bite], individuals with [Type 2 diabetes] can effectively control their [blood glucose levels] and navigate the challenging landscape of their condition with greater confidence. It's a simple yet impactful change that can make a world of difference in the lives of those living with [diabetes].

Date :
  1. Date Completed 1996-03-21
  2. Date Revised 2019-08-30
Further Info :

Pubmed ID

8582130

DOI: Digital Object Identifier

10.1111/j.1464-5491.1995.tb00409.x

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Languages

English

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