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[Effect of topical adrenergic agents on tissue circulation in human optic nerve head evaluated with a laser speckle microcirculation analyser].

Author: AraieM, NagaharaM, TamakiY, TomidokoroA, TomitaK

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated the effects of carteolol and dipivefrine on tissue circulation in the human optic nerve head. A single instillation of carteolol significantly increased tissue blood velocity in the optic nerve head, while dipivefrine did not have a significant effect. Both drugs reduced intraocular pressure. These results suggest that carteolol may improve blood flow to the optic nerve head, while dipivefrine has no effect on blood flow in this area.
Paper Details　
Original Abstract of the Article :
The effects of a single instillation of 2% carteolol or 0.1% dipivefrine on the tissue circulation in the human optic nerve head (ONH) was studied using a laser speckle tissue circulation analyser in 12 healthy volunteers. In the first experiment, normalized blur (NB), a quantitative index of periph...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8644530

データ提供：米国国立医学図書館（NLM）

[Effect of topical adrenergic agents on tissue circulation in human optic nerve head evaluated with a laser speckle microcirculation analyser]

This study delves into the intricate world of ocular circulation, exploring the effects of specific medications on the blood flow to the optic nerve head, a crucial part of the eye. It's like studying the flow of a hidden underground river in a desert, trying to understand how its movements affect the surrounding oasis. The researchers used a laser speckle microcirculation analyser to investigate the effects of topical carteolol and dipivefrine on the blood flow to the optic nerve head. They carefully observed the changes in blood velocity after applying these medications, akin to tracing the path of the river and measuring its speed. The study found that carteolol, an eye drop medication, increased blood flow to the optic nerve head, suggesting a potential benefit for eye health.

The Potential for Improved Eye Health

This study suggests that carteolol may be beneficial for maintaining eye health, potentially helping to improve blood flow to the optic nerve head. It's like finding a way to increase the flow of water to an oasis, nourishing the plants and ensuring its continued prosperity.

The Importance of Further Research

While the findings are promising, further research is needed to confirm the long-term effects of carteolol on ocular circulation and its potential to prevent or treat eye diseases. It's like a desert explorer who continues to investigate the underground river system, seeking a deeper understanding of its impact on the surrounding environment.

Dr. Camel's Conclusion

This study highlights the importance of understanding the intricate network of blood flow within the eye and its impact on eye health. It's a reminder that even in the seemingly simple organ of the eye, there are complex systems at work, like the hidden pathways of water in a vast desert.
Date :
  1. Date Completed 1996-07-12
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

8644530

DOI: Digital Object Identifier

8644530

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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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