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Risk of new primaries after chemotherapy and/or tamoxifen treatment for early breast cancer.

Author: BoccardoF, CasellaC, PerrottaA, RubagottiA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigates the incidence of new cancers in patients with early-stage breast cancer who received either chemotherapy, tamoxifen, or a combination of both after mastectomy. While both treatments have been shown to cause cancer in laboratory models, there is limited data on their impact on developing new cancers in humans with breast cancer. The study aims to provide more information about the risk of developing new cancers after these treatments.
Paper Details　
Original Abstract of the Article :
Both chemotherapy and tamoxifen are widely used either alone or in combination as adjuvant treatment following mastectomy. Despite the fact that both of them exhibit carcinogenic properties in experimental models, detailed reports on the incidence of new primaries following chemotherapy and/or tamox...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8740786

データ提供：米国国立医学図書館（NLM）

Chemotherapy and Tamoxifen: Exploring the Risk of New Primaries

Breast cancer, a prevalent disease affecting women worldwide, often requires aggressive treatment, including chemotherapy and tamoxifen. This research delves into the potential risks associated with these treatments, specifically the possibility of developing new primary cancers.

Navigating Treatment: Understanding the Potential Side Effects

The researchers highlight the need for more extensive data on the incidence of new primary cancers after chemotherapy and/or tamoxifen treatment. While these therapies are effective in treating breast cancer, they can also have unintended consequences. The research underscores the importance of careful monitoring and long-term follow-up for patients undergoing these treatments.

Informed Decision-Making: Balancing Benefits and Risks

This research emphasizes the need for informed decision-making in cancer treatment. Patients should discuss the potential risks and benefits of various treatment options with their doctor to determine the best course of action. While these therapies offer hope for survival, it is crucial to be aware of the potential for long-term side effects.

Dr. Camel's Conclusion

Like a desert oasis, cancer treatment can be a life-saving haven. However, it's important to understand the potential side effects of the treatment, like a hidden dune threatening to shift the landscape. This research emphasizes the need for comprehensive data on the long-term consequences of these treatments to make informed decisions and navigate the journey with awareness.
Date :
  1. Date Completed 1996-11-05
  2. Date Revised 2020-02-03
Further Info :

Pubmed ID

8740786

DOI: Digital Object Identifier

S0923-7534(20)31793-2

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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