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A sequential trial of viloxazine (Vivalan) and imipramine in moderately depressed patients.

Author: BurrowsG, DaviesB, JoshuaS, PoyntonC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Viloxazine and imipramine were compared for their effectiveness in treating moderately severe depressive illness in 22 patients. Both treatments resulted in significant reductions in depression scores. No significant difference was found between the two treatments, but fewer side effects were reported with viloxazine.
Paper Details　
Original Abstract of the Article :
Patients with moderately severe depressive illness were matched for age, sex, severity of symptoms and number of previous episodes of affective illness. Eleven pairs of patients were randomly assigned to four weeks' treatment with either viloxazine (100 mg three times a day) or imipramine (50 mg thr...See full text at original site
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引用元：
https://doi.org/10.5694/j.1326-5377.1977.tb130866.x

データ提供：米国国立医学図書館（NLM）

Viloxazine vs. Imipramine: A Sequential Trial in Moderately Depressed Patients

[Depression] is a complex mental health condition that can have a significant impact on a person's life. This study compares the effectiveness of two different medications, [viloxazine] and [imipramine], for treating [moderately depressed] patients. This is like testing two different methods of navigating through a sandstorm - each approach may lead to different outcomes.

Viloxazine: A Promising Alternative for Depression Treatment

The study found that both medications were effective in reducing symptoms of [depression]. However, [viloxazine] was associated with significantly fewer side effects. This is like finding a path through the desert that leads to a refreshing oasis without encountering any treacherous sand dunes along the way. This suggests that [viloxazine] might be a preferable treatment option for some patients.

Treating Depression: Finding the Right Route Through a Mental Health Desert

This study underscores the importance of finding the right medication for each individual patient suffering from [depression]. This is like carefully choosing the path through the desert that best suits our individual needs and abilities. Further research is needed to explore the long-term effects of [viloxazine] and [imipramine] and to develop more personalized treatment approaches for [depression].

Dr. Camel's Conclusion

This study provides a valuable comparison of two different medications for [depression]. While both medications showed positive results, [viloxazine]'s superior side effect profile suggests it might be a suitable alternative for some patients. This is like discovering a new and easier path through the desert, offering a more comfortable and effective journey for those seeking relief from the challenges of [depression]. As researchers continue to explore the complexities of [depression], we can anticipate even more effective treatments that offer hope and healing for those who suffer from this condition.
Date :
  1. Date Completed 1977-08-25
  2. Date Revised 2021-03-13
Further Info :

Pubmed ID

875786

DOI: Digital Object Identifier

10.5694/j.1326-5377.1977.tb130866.x

Related Literature

Article Analysis
・Side Effects of viloxazine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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