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Changes in synovial membrane and joint effusion volumes after intraarticular methylprednisolone. Quantitative assessment of inflammatory and destructive changes in arthritis by MRI.

Author: GideonP, HenriksenO, LorenzenI, OstergaardM, StoltenbergM, SørensenK

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Synovial membrane and effusion volumes decreased significantly in the first week after treatment, and remained low during remission. The synovial volume, but not the effusion volume, increased to pretreatment levels in case of clinical relapse, indicating that synovial volumes are most important to the clinical appearance. The study concluded that MRI-determined synovial and effusion volumes, and MRI scores of cartilage and bone erosions, are reproducible and may be sensitive measures of disease activity and severity in rheumatoid arthritis.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate synovial membrane volumes, effusion volumes, and cartilage and bone erosion scores determined by magnetic resonance imaging (MRI) as markers of disease activity and severity in arthritis. METHODS: Gadolinium-DTPA enhanced MRI of 18 arthritic knees was performed before and 1, ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8823685

データ提供：米国国立医学図書館（NLM）

MRI: A Guiding Compass in the Desert of Arthritis

The field of [arthritis] is a vast and complex desert, where researchers are constantly seeking new ways to diagnose and manage this painful condition. This research investigates the use of [magnetic resonance imaging (MRI)] to assess the severity and progression of [arthritis], seeking a more accurate and comprehensive tool to guide treatment decisions. The authors used [MRI] to measure changes in [synovial membrane volume, effusion volume, cartilage erosion, and bone erosion] in patients with [arthritis], hoping to find a guiding compass in the desert of inflammation.

A Clearer Picture in the Desert: MRI Reveals Hidden Details of Arthritis

The study found that [MRI] can provide valuable insights into the severity and progression of [arthritis], offering a more detailed and nuanced understanding of the condition than traditional methods. The authors highlight the ability of [MRI] to detect changes in [synovial membrane volume and effusion volume], as well as subtle signs of [cartilage and bone erosion], which may not be visible on X-rays. It's like using a powerful telescope to explore the hidden details of a distant desert landscape.

Navigating the Shifting Sands: Using MRI to Guide Treatment Decisions

This research underscores the importance of [MRI] in the diagnosis and management of [arthritis]. It provides a more accurate and comprehensive assessment of disease activity and severity, allowing for more targeted and effective treatment strategies. It's like having a reliable compass to guide us through the shifting sands of inflammation, leading to better outcomes for patients.

Dr.Camel's Conclusion

This study reminds us that the desert of arthritis can be navigated with the right tools and techniques. MRI provides a clearer picture of the disease landscape, allowing us to make more informed decisions about treatment and improve the lives of patients.

Date :
  1. Date Completed 1996-12-18
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8823685

DOI: Digital Object Identifier

8823685

Related Literature

Article Analysis
・Effects of methylprednisolone injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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