Early institution of bromocriptine in Parkinson's disease inhibits the emergence of levodopa-associated motor side effects. Long-term results of the PRADO study.

Author: BlümnerE, DanielczykW, GerlachM, KaiserH J, KrausP H, LetzelH, PrzuntekH, RiedererP, UberlaK, WelzelD

Paper Details 
Original Abstract of the Article :
Long-term levodopa treatment in Parkinson's disease is typically associated with "motor side effects" consisting in dyskinesias and/or fluctuations in motility referred to as the on-off phenomena. The main objective of this prospective, randomized, multi-centre study was to determine to what extent ...See full text at original site
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引用元:
https://doi.org/10.1007/BF01271230

データ提供:米国国立医学図書館(NLM)

Preventing Parkinson's Disease Complications: A New Strategy

Parkinson's disease, a neurodegenerative disorder, can be a challenging journey. Like a desert traveler facing the harsh realities of the environment, patients with Parkinson's disease often experience motor complications related to long-term levodopa treatment. This study explored a new strategy to prevent the development of these complications by partially replacing levodopa with bromocriptine in patients with early-stage Parkinson's disease.

Early Intervention with Bromocriptine

This long-term, randomized, multi-center study found that partial substitution of levodopa with bromocriptine in patients with early-stage Parkinson's disease significantly reduced the risk of developing motor side effects. The study results suggest that early intervention with bromocriptine could potentially extend the period of optimal disease control. The results are like finding a reliable water source in the desert, offering a chance for patients to manage their disease effectively.

Managing Parkinson's Disease

This study emphasizes the importance of early intervention in managing Parkinson's disease. By understanding the potential benefits of bromocriptine, patients and their doctors can work together to create a personalized treatment plan that minimizes the risk of complications. This study, like a compass guiding a traveler through the desert, provides a new direction for managing Parkinson's disease.

Dr. Camel's Conclusion

This study explores the potential of bromocriptine as a preventative measure for levodopa-associated motor side effects in patients with early-stage Parkinson's disease. Like a desert traveler using a camel's hump for sustenance, this research reveals that early intervention with bromocriptine could provide a valuable resource for managing the disease effectively.

Date :
  1. Date Completed 1996-12-17
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

8836932

DOI: Digital Object Identifier

10.1007/BF01271230

Related Literature

SNS
PICO Info
in preparation
Languages

English

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