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Effects of benazepril and nicardipine on microalbuminuria in normotensive and hypertensive patients with diabetes.

Author: AndrianiA, BertocchiF, BonfantinoM V, CavalloA, De CesarisR, LamontanaraG, RanieriG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Benazepril was more effective than nicardipine in reducing overnight microalbuminuria in patients with diabetes mellitus, independently of their antihypertensive properties.
Paper Details　
Original Abstract of the Article :
Diabetic nephropathy is the most frequent cause of chronic renal failure. The onset of microalbuminuria in patients with diabetes mellitus, which seems to be related to blood pressure and the control of glycemia, is predictive of the development of true proteinuria. This multicenter, single-blind, r...See full text at original site
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引用元：
https://doi.org/10.1016/S0009-9236(96)90204-0

データ提供：米国国立医学図書館（NLM）

Benazepril vs. Nicardipine: Navigating the Desert of Diabetic Nephropathy

Diabetic nephropathy, a serious complication of diabetes, poses a significant threat to kidney health. This study, like a camel traversing a treacherous desert, embarks on a quest to evaluate the effectiveness of two medications, benazepril and nicardipine, in managing microalbuminuria, an early sign of diabetic nephropathy. The researchers meticulously analyzed the effects of these medications on patients with diabetes, both normotensive and hypertensive.

Benazepril Emerges as a Potential Oasis in the Desert of Diabetic Nephropathy

This study found that benazepril was more effective than nicardipine in reducing microalbuminuria in diabetic patients, regardless of their blood pressure status. The research suggests that benazepril may offer a more potent therapeutic option for managing early signs of diabetic nephropathy, offering a potential oasis in the desert of kidney complications. This finding underscores the importance of tailoring treatment strategies based on individual patient needs.

Protecting Your Kidneys: A Desert Oasis of Effective Management

This research provides valuable insights into the management of diabetic nephropathy, a potentially devastating complication. The study highlights the importance of early intervention and personalized treatment approaches to protect kidney health. By understanding the nuances of diabetic nephropathy and the effectiveness of different medications, we can better manage this condition and improve patient outcomes.

Dr. Camel's Conclusion

Diabetic nephropathy can be a challenging journey, but this study points toward a potential path for effective management. Benazepril, like a desert oasis, offers a beacon of hope for those seeking to mitigate the risks of this devastating condition. Remember, prevention is key, and careful management of diabetes is crucial for protecting kidney health.

Date :
  1. Date Completed 1996-11-27
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

8873695

DOI: Digital Object Identifier

10.1016/S0009-9236(96)90204-0

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Languages

English

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