Mood effects of zolpidem versus phenobarbital combined with promethazine in an anesthesiological setting.

Author: HüppeM, NidermaierB, PestelG, UhligT

Paper Details 
Original Abstract of the Article :
Zolpidem, a new imidazo-pyridine hypnotic, acts like a benzodiazepine. Because of its short half-life, zolpidem plays a special role in the group of drugs suitable for anesthesiological premedication because of its sedative and anxiolytic effects. The study compared preanesthesiological treatment by...See full text at original site
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引用元:
https://doi.org/10.1159/000119298

データ提供:米国国立医学図書館(NLM)

Zolpidem and Phenobarbital: A Comparative Look at Mood Effects

Pre-anesthetic medications play a vital role in preparing patients for surgical procedures, aiming to minimize anxiety and discomfort. This study compares the mood effects of two pre-anesthetic medications: zolpidem, a new imidazo-pyridine hypnotic, and phenobarbital, a long-established sedative. The study employs a double-blind, randomized design to compare the effects of these two medications on emotional states in patients awaiting surgery.

Distinctive Mood Effects: A Closer Look

The study reveals that zolpidem and phenobarbital have distinct effects on mood, particularly in the domains of irritation, vulnerability, and aggression. The study observes that zolpidem, while exhibiting sedative effects similar to phenobarbital, has a different impact on mood, potentially offering a more favorable profile for some patients.

Personalized Pre-anesthesia Care: Tailoring Treatment to Individual Needs

This study underscores the importance of considering individual patient needs when choosing pre-anesthetic medications. The study highlights the potential for zolpidem to offer a more favorable mood profile compared to phenobarbital. The findings suggest that tailoring pre-anesthetic medications to individual needs can contribute to a more positive and comfortable experience for patients undergoing surgical procedures.

Dr. Camel's Conclusion

This study provides valuable insights into the mood effects of different pre-anesthetic medications. The study's findings highlight the importance of considering individual patient needs when choosing medications, aiming to optimize patient comfort and well-being. The desert of medical knowledge is vast, and ongoing research is crucial to identify the most effective treatments for individual patients.

Date :
  1. Date Completed 1997-02-12
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

8904738

DOI: Digital Object Identifier

10.1159/000119298

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SNS
PICO Info
in preparation
Languages

English

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