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Treatment of the hyperventilation syndrome with bisoprolol: a placebo-controlled clinical trial.

Author: HoesM J, MouthaanB J, Van De VenL L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Bisoprolol was effective in reducing the number and severity of hyperventilation attacks in patients with hyperventilation syndrome. No serious side effects were reported.
Paper Details　
Original Abstract of the Article :
The hyperventilation syndrome (HVS) can be regarded as a form of panic disorder associated with a relative increase in sympathomimetic tone, the effects of which can be counterbalanced by beta-adrenoceptor blockade. The efficacy of the beta-blocker bisoprolol was investigated in a double-blind place...See full text at original site
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引用元：
https://doi.org/10.1016/0022-3999(95)00508-0

データ提供：米国国立医学図書館（NLM）

Treatment of the hyperventilation syndrome with bisoprolol: a placebo-controlled clinical trial

This research explores the potential effectiveness of bisoprolol, a beta-blocker, in managing hyperventilation syndrome (HVS), a condition characterized by excessive breathing and associated symptoms like dizziness, anxiety, and chest tightness. The study utilizes a double-blind, placebo-controlled crossover trial to evaluate the efficacy of bisoprolol compared to placebo in reducing the frequency and severity of HVS attacks.

Bisoprolol Demonstrates Significant Benefits in HVS Management

The study's findings demonstrate that bisoprolol is effective in reducing the number and severity of HVS attacks. Compared to placebo, bisoprolol significantly decreased the number of attacks per week and improved the severity of symptoms. This suggests that bisoprolol may be a valuable treatment option for patients with HVS who experience frequent and debilitating attacks.

Addressing the Underlying Sympathetic Nervous System Hyperactivity

This research highlights the potential role of beta-blockers in managing HVS. HVS is often associated with an increased sympathetic nervous system tone, and bisoprolol, by blocking beta-adrenergic receptors, can help to counterbalance this hyperactivity, reducing the symptoms of HVS. As a desert dweller, I can relate to the importance of balance in maintaining equilibrium, and this study emphasizes the same principle in the context of managing HVS.

Dr.Camel's Conclusion

This study provides evidence for the effectiveness of bisoprolol in reducing the frequency and severity of hyperventilation syndrome attacks. The findings suggest that bisoprolol may be a valuable treatment option for individuals experiencing frequent and debilitating HVS symptoms. Just as a desert traveler seeks out a wellspring to quench their thirst, this research offers a potential oasis of relief for those struggling with HVS.

Date :
  1. Date Completed 1996-10-29
  2. Date Revised 2019-08-30
Further Info :

Pubmed ID

8926595

DOI: Digital Object Identifier

10.1016/0022-3999(95)00508-0

Related Literature

Article Analysis
・Side Effects of bisoprolol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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