Paper Details

  1. Home
  2. Paper Details

Secondary preventive potential of lipid-lowering drugs. The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT).

Author: EricssonC G, GripL, HamstenA, NilssonJ, SvaneB, de FaireU

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study investigated the effectiveness of bezafibrate in slowing the progression of coronary atherosclerosis in young male survivors of myocardial infarction. Bezafibrate was shown to slow the progression of focal coronary atherosclerosis to a degree comparable to statins and also reduced the occurrence of coronary events.
Paper Details　
Original Abstract of the Article :
Current experience from coronary angiographic trials using different treatment regimens such as lifestyle changes, resins, nicotinic acid and statins, shows that progression of atheroma can be retarded, and that regression can sometimes be induced, by a marked lowering of LDL-cholesterol. Young post...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1093/eurheartj/17.suppl_f.37

データ提供：米国国立医学図書館（NLM）

Bezafibrate: A Sandstorm of Hope in the Desert of Coronary Atherosclerosis

Coronary atherosclerosis, like a relentless sandstorm, can choke the life out of our heart’s arteries. The quest for effective treatments that can slow or reverse this process is paramount. This study, like a caravan traversing a challenging desert, explores the potential of bezafibrate, a lipid-lowering drug, in mitigating the progression of coronary atherosclerosis. The researchers, like skilled desert navigators, carefully monitored the effects of bezafibrate on young patients who had recently experienced a heart attack.

Bezafibrate: A Potential Solution for Coronary Atherosclerosis

The results, like a refreshing oasis in the desert, showed that bezafibrate was effective in slowing the progression of coronary atherosclerosis in young patients. The study found that bezafibrate not only reduced cholesterol and triglyceride levels but also lowered fibrinogen levels, a protein that promotes blood clotting. These findings suggest that bezafibrate could play a crucial role in preventing future heart events in young patients with coronary atherosclerosis.

Navigating the Landscape of Heart Health: Taking Action for Prevention

This study underscores the importance of taking proactive steps to prevent heart disease. Maintaining a healthy lifestyle, including a balanced diet and regular exercise, is crucial for reducing the risk of coronary atherosclerosis. Regular checkups with a healthcare professional can help identify early signs of heart disease and allow for timely intervention. Like a seasoned desert traveler, it’s important to be vigilant and proactive in protecting our heart health.

Dr.Camel's Conclusion

Bezafibrate shows promise as a treatment for coronary atherosclerosis. This study highlights the importance of preventing and managing heart disease, like navigating a challenging desert with care and foresight.

Date :
  1. Date Completed 1997-03-13
  2. Date Revised 2019-05-12
Further Info :

Pubmed ID

8960446

DOI: Digital Object Identifier

10.1093/eurheartj/17.suppl_f.37

Related Literature

Article Analysis
・Effective treatment of atherosclerosis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.