Paper Details

  1. Home
  2. Paper Details

Clozapine's effectiveness for patients in state hospitals: results from a randomized trial.

Author: CovellN H, EssockS M, GoetheJ, HargreavesW A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).

Overview

Clozapine was associated with significantly greater reductions in side effects, disruptiveness, and hospitalization, but was not more effective in reducing symptoms or improving quality of life.
Paper Details　
Original Abstract of the Article :
In our study, we examined the effectiveness of clozapine and compared it to the array of medication alternatives typically used in the public sector. Long-term patients in Connecticut's state hospitals who met Food and Drug Administration criteria for clozapine use were invited to participate in thi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/8993092

データ提供：米国国立医学図書館（NLM）

Clozapine's Effectiveness in State Hospitals: A Randomized Trial

This research evaluates the effectiveness of clozapine, a medication used to treat schizophrenia, in a real-world setting: state hospitals. The study compares the outcomes of clozapine treatment to the usual care provided in these facilities. The research findings suggest that clozapine can be an effective treatment option for patients with schizophrenia, leading to reductions in side effects, disruptiveness, and hospitalizations. While clozapine did not significantly improve symptoms or quality of life, it did reduce the likelihood of readmission after discharge.

Clozapine: A Promising Treatment Option for Schizophrenia in State Hospitals

This study provides valuable insights into the effectiveness of clozapine for schizophrenia patients in state hospitals. The research demonstrates that clozapine can be a beneficial treatment option, leading to reductions in side effects, disruptiveness, and hospitalizations. While clozapine did not significantly improve symptoms or quality of life, it did reduce the likelihood of readmission after discharge. These findings highlight the potential benefits of clozapine in managing schizophrenia in a real-world setting.

Navigating the Treatment of Schizophrenia: Real-World Considerations

This research emphasizes the importance of considering real-world factors when evaluating the effectiveness of treatments for schizophrenia. The study highlights the challenges of managing this complex condition in a state hospital setting. While clozapine showed promise in reducing side effects and hospitalizations, it did not significantly improve symptoms or quality of life. This research underscores the need for ongoing research to develop more effective treatments for schizophrenia and to improve the quality of care for patients in state hospitals.

Dr. Camel's Conclusion

Imagine a desert oasis, where the shimmering water represents the hope of recovery for schizophrenia patients. Clozapine, like a life-giving well, provides relief from some of the challenges of this complex condition. While clozapine may not offer a complete solution, it offers valuable support for patients in state hospitals, helping them navigate the desert of their illness and find moments of respite.

Date :
  1. Date Completed 1997-02-12
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8993092

DOI: Digital Object Identifier

8993092

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.