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Acute reinforcing effects of low-dose nicotine nasal spray in humans.
Author: CaggiulaA, GrobeJ E, PerkinsK A, StillerR L, WilsonA S
Original Abstract of the Article :
Tobacco smoking behavior is reinforced by nicotine intake, but there has been little human research examining self-administration of nicotine per se, isolated from tobacco. In this study, 10 smokers (5 men, 5 women) who wanted to quit smoking sampled 0 (placebo), 0.75, and 1.5 ug/kg/spray nicotine v...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元：
https://doi.org/10.1016/s0091-3057(96)00216-x
データ提供：米国国立医学図書館（NLM）
Low-Dose Nicotine Nasal Spray: Exploring the Desert of Nicotine Reinforcement
This study investigates the reinforcing effects of low-dose nicotine nasal spray in humans. The researchers examined the self-administration of nicotine nasal spray in 10 smokers, independent of tobacco smoking. The study found that while the majority of participants did not self-administer nicotine nasal spray significantly more than placebo, a subset of participants (4 out of 10) showed a preference for the higher nicotine dose, suggesting that nicotine, even in the absence of tobacco, can be reinforcing for some smokers. This research provides valuable insights into the reinforcing properties of nicotine, offering a glimpse into the complex mechanisms of addiction. This study is like a journey through the desert of nicotine reinforcement, revealing the intricate interplay of individual responses and the addictive properties of nicotine.
Nicotine: A Complex and Enigmatic Oasis
The study's findings suggest that nicotine, even in the absence of tobacco, can be reinforcing for some smokers. This research highlights the complex and multifaceted nature of nicotine addiction, offering a deeper understanding of the factors that contribute to its powerful hold. This research is a reminder that in the vast desert of addiction, there are many hidden oases of complexity and enigma, waiting to be explored.
Navigating the Complexities of Nicotine Addiction
This research provides valuable insights into the reinforcing properties of nicotine, reminding us that addiction is a complex phenomenon with individual variations. The study's findings encourage further research into the mechanisms of nicotine reinforcement, offering potential pathways for developing more effective treatments for nicotine addiction. This study is a testament to the ongoing quest to understand and combat nicotine addiction, a reminder that in the vast desert of this condition, there may be many hidden oases of knowledge waiting to be discovered.
Dr.Camel's Conclusion
This research provides a glimpse into the reinforcing properties of nicotine, highlighting the complex and multifaceted nature of nicotine addiction. The study's findings encourage further exploration of the mechanisms of nicotine reinforcement, offering potential pathways for developing more effective treatments for nicotine addiction.
Date :
- Date Completed 1997-05-01
- Date Revised 2019-12-10
Further Info :
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