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Breast cancer.

Author: RutqvistL E

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Radiation therapy is crucial in preventing breast cancer from returning after surgery. It is more effective than chemotherapy after both mastectomy and breast-conserving surgery, particularly for patients with lymph node involvement, where it reduces the risk of the cancer spreading and death from breast cancer. While radiation therapy alone may not increase overall survival, as its benefits are counteracted by an increased risk of heart problems, it can improve survival when combined with other treatments, like chemotherapy or hormone therapy. Modern techniques have reduced the risk of heart problems associated with radiation therapy. Radiation therapy is also used to reduce recurrence after breast-conserving surgery for DCIS (ductal carcinoma in situ) and to relieve symptoms in patients with advanced breast cancer. Further research is needed to identify patients who may not require routine radiation therapy or who may benefit from different approaches, like surgery instead of breast-conserving therapy.
Paper Details　
Original Abstract of the Article :
This synthesis of the literature on radiotherapy for breast cancer is based on 97 scientific articles, including 5 meta-analyses, 38 randomized studies, and 27 retrospective studies. These studies involve 387634 patients. Radiotherapy is the most effective method for preventing locoregional recurren...See full text at original site
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引用元：
https://doi.org/10.3109/02841869609101663

データ提供：米国国立医学図書館（NLM）

Radiotherapy for Breast Cancer: A Comprehensive Review

The battle against [breast cancer] has been a long and arduous journey, with countless researchers dedicating their lives to finding effective treatments. This extensive review, summarizing data from 97 scientific articles involving over 387,000 patients, provides a comprehensive overview of [radiotherapy] and its role in breast cancer management.

The study emphasizes the crucial role of radiotherapy in preventing the recurrence of breast cancer after surgery. In fact, it is considered more effective than [chemotherapy] in many cases. However, the research also acknowledges that while radiotherapy can significantly improve [relapse-free survival] and reduce the risk of distant metastasis, its impact on overall survival is more complex. This is due to the fact that the benefits of radiotherapy in reducing breast cancer mortality may be offset by an increase in cardiovascular disease mortality, especially in cases involving high doses of radiation.

Radiotherapy: A Vital Weapon in the Fight Against Breast Cancer

The data clearly demonstrate the effectiveness of radiotherapy in preventing locoregional recurrence after surgery. It's like a skilled archer aiming to prevent any stray arrows from returning to the target. This finding underscores the importance of radiotherapy as a standard treatment approach for breast cancer.

Balancing Benefits and Risks: A Careful Approach to Radiation Therapy

The review highlights the critical need for a balanced approach to radiotherapy. While it offers significant benefits, it also carries potential risks, particularly to the heart. The use of modern treatment techniques and careful dose planning is essential to minimize these risks. It's like navigating a vast desert, where careful planning and resource management are crucial to avoid dehydration and other dangers.

Dr.Camel's Conclusion

This comprehensive review provides invaluable insights into the effectiveness and potential risks of radiotherapy for breast cancer. It reminds us that progress in healthcare involves constant refinement and innovation. The ongoing research in this field will continue to shape the future of breast cancer treatment, enabling us to offer patients the best possible chance for a healthy and fulfilling life.

Date :
  1. Date Completed 1997-06-11
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

9154095

DOI: Digital Object Identifier

10.3109/02841869609101663

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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