Optimizing the intragastric pH as a supportive therapy in upper GI bleeding.

Author: BrunnerG, HartmannM, LunaP, WurstW

Paper Details 
Original Abstract of the Article :
Acid inhibitory therapy has long been considered of no benefit for upper GI bleeding. The reason was that achlorhydria in the stomach could not be achieved with any single or combination of acid inhibitory drugs. The introduction of proton pump inhibitors has, for the first time, allowed the physici...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2589014/

データ提供:米国国立医学図書館(NLM)

Achlorhydria: A New Oasis in the Desert of Upper GI Bleeding

The treatment of upper gastrointestinal (GI) bleeding is a complex landscape, much like a vast desert. This study, published in the journal '[Journal Name]', explores a novel approach to managing this challenging condition: optimizing intragastric pH. The authors investigated the potential benefits of achieving achlorhydria, a state of low stomach acid, using high doses of intravenously administered proton pump inhibitors.

The study found that achieving an intragastric pH of near 7, a state similar to the refreshing coolness of a desert oasis, significantly improved clinical outcomes in patients with upper GI bleeding. The researchers demonstrated the efficacy of large doses of proton pump inhibitors in achieving this pH, highlighting the importance of controlling stomach acid in managing this condition.

Navigating the Desert of Upper GI Bleeding

This study offers a valuable insight into the potential of achlorhydria as a therapeutic target for upper GI bleeding. The study's findings suggest that achieving an optimal intragastric pH can significantly improve patient outcomes. This discovery is a testament to the power of targeted therapies in managing complex medical conditions.

The Importance of Hydration

The desert of the stomach can be a harsh environment for patients experiencing upper GI bleeding. Optimizing intragastric pH, similar to finding a refreshing oasis, can help create a more favorable environment for healing. This study emphasizes the importance of maintaining a balanced environment in the body for optimal health and recovery.

Dr.Camel's Conclusion

This study offers a valuable contribution to the field of upper GI bleeding management. The research demonstrates the potential of achlorhydria as a therapeutic target, highlighting the importance of controlling stomach acid in achieving optimal clinical outcomes. The findings remind us that even in the challenging desert of complex medical conditions, targeted therapies can offer valuable solutions.

Date :
  1. Date Completed 1997-07-29
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

9165691

DOI: Digital Object Identifier

PMC2589014

Related Literature

SNS
PICO Info
in preparation
Languages

English

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