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[Effectiveness and tolerance of tramadol in cancer pain. A comparative study with respect to buprenorphine].

Author: BonoA V, CuffariS

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Tramadol, a new opioid analgesic, was found to be as effective as buprenorphine in relieving pain in patients with advanced cancer. Tramadol was better tolerated than buprenorphine, with fewer and milder adverse reactions. Only 1 patient discontinued tramadol, compared with 18 using buprenorphine.
Paper Details　
Original Abstract of the Article :
Opioid analgesics represent one of the most important tools in a sequential pharmacological approach to oncological pain relief. They are recommended by the WHO when nonsteroidal anti-inflammatory drugs (NSAIDs) no longer provide adequate analgesia. However, the use of opioids is limited because of ...See full text at original site
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引用元：
https://doi.org/10.2165/00003495-199700532-00009

データ提供：米国国立医学図書館（NLM）

Tramadol: A New Hope for Cancer Pain Management

Managing pain effectively is crucial for patients with cancer. This study explores the efficacy and tolerability of tramadol, a new analgesic, compared to buprenorphine, a commonly used opioid, in relieving cancer pain. Think of it like comparing two types of water sources in a desert – one might be more refreshing and less harsh than the other.

Comparing Analgesics in the Desert of Pain

The researchers conducted a controlled trial with patients experiencing advanced cancer pain, comparing the effectiveness of tramadol and buprenorphine. They found that both drugs provided significant pain relief, but tramadol was more effective in reducing pain within one hour of administration and was better tolerated by patients, with fewer side effects. It's like finding a spring of water that quenches thirst more quickly and provides a more pleasant experience compared to another source.

A More Tolerable Approach to Pain Relief

This research suggests that tramadol may be a valuable alternative to buprenorphine in managing cancer pain. It's like discovering a new oasis in the desert – providing a more comfortable and effective way to combat the challenges of pain.

Dr. Camel's Conclusion

This study demonstrates the potential of tramadol as an effective and well-tolerated treatment option for cancer pain, providing a new avenue for improving the quality of life for patients battling this challenging disease.

Date :
  1. Date Completed 1997-06-19
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

9190324

DOI: Digital Object Identifier

10.2165/00003495-199700532-00009

Related Literature

Article Analysis
・Effects of tramadol
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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