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Original Abstract of the Article :
Dolasetron (dolasetron mesilate) is a pseudopelletierine-derived 5-HT3 antagonist which has recently become available for clinical use. It is rapidly converted in vivo to its active major metabolite, hydrodolasetron, which appears to be largely responsible for its pharmacological activity. In clinic...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2165/00003495-199754020-00008
データ提供:米国国立医学図書館(NLM)
Dolasetron: A New Oasis in the Desert of Nausea and Vomiting
Nausea and vomiting, often triggered by chemotherapy, radiotherapy, or surgery, can significantly impact a patient's quality of life. This study, like a camel caravan seeking a respite from the scorching desert sun, explores the therapeutic potential of dolasetron, a 5-HT3 antagonist, in managing these debilitating side effects.
The authors comprehensively review the pharmacology and clinical applications of dolasetron. They detail its effectiveness in preventing and treating chemotherapy-induced nausea and vomiting (CINV), radiotherapy-induced nausea and vomiting (RINV), and postoperative nausea and vomiting (PONV).
Dolasetron: A Potential Solution for Nausea and Vomiting
Dolasetron has demonstrated efficacy in preventing and treating various forms of nausea and vomiting. It has been shown to be effective in both intravenous and oral formulations. The study also highlights the favorable tolerability profile of dolasetron, making it a promising option for patients experiencing these debilitating side effects.
Navigating the Desert of Nausea and Vomiting Management
This review provides a valuable resource for healthcare providers seeking to manage nausea and vomiting in their patients. It highlights the potential benefits of dolasetron and encourages further research to explore its optimal dosing and efficacy in different clinical settings.
Dr.Camel's Conclusion
The study suggests that dolasetron may provide a welcome oasis in the desert of nausea and vomiting. Its ability to effectively manage these debilitating side effects could significantly improve the quality of life for patients undergoing various treatments.
Date :
- Date Completed 1997-09-08
- Date Revised 2022-07-16
Further Info :
Related Literature
English
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