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Midazolam: a review of therapeutic uses and toxicity.

Author: ClarkR F, NordtS P

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Midazolam, a benzodiazepine, is a safe and effective agent for sedation in the emergency department. It has a rapid onset of action and can be administered via various routes. Potential adverse effects include respiratory depression, particularly when used with opioids.
Paper Details　
Original Abstract of the Article :
Midazolam is a familiar agent commonly used in the emergency department to provide sedation prior to procedures such as laceration repair and reduction of dislocations. Midazolam is also effective in the treatment of generalized seizures, status epilepticus, and behavioral emergencies, particularly ...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/s0736-4679(97)00022-x

データ提供：米国国立医学図書館（NLM）

Midazolam: A Versatile Sedative with Potential Risks

Midazolam, a common sedative used in emergency departments, is a powerful tool for managing a variety of situations. This study, like a desert guide sharing knowledge with travelers, provides a comprehensive overview of midazolam's therapeutic uses, as well as its potential risks. The study emphasizes midazolam's rapid onset of action and its effectiveness in treating seizures, status epilepticus, and behavioral emergencies. However, it also highlights the importance of careful monitoring for respiratory depression, particularly when used in combination with opioids.

Midazolam's Uses and Cautions

Midazolam's versatility makes it a valuable tool in emergency medicine, but its potential risks should be carefully considered. The study's findings underscore the importance of proper patient selection, careful dose titration, and close monitoring for adverse effects.

Navigating Sedation in Emergency Settings

The use of midazolam in emergency settings requires a delicate balance between its therapeutic benefits and its potential risks. This study provides valuable guidance for clinicians, reminding them to navigate the desert of emergency medicine with caution and vigilance.

Dr. Camel's Conclusion

Midazolam, like a powerful but potentially dangerous desert plant, can be a valuable resource when used wisely. This study provides a comprehensive overview of its uses and risks, reminding us that even the most effective tools require careful handling and respect. As always, knowledge is power, and understanding the nuances of medication use is essential for safe and effective patient care.

Date :
  1. Date Completed 1997-09-26
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

9258787

DOI: Digital Object Identifier

10.1016/s0736-4679(97)00022-x

SNS
PICO Info
in preparation
Languages

English

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