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High-dose pyridoxine and magnesium administration in children with autistic disorder: an absence of salutary effects in a double-blind, placebo-controlled study.

Author: FindlingR L, HuangJ, MaxwellK, Scotese-WojtilaL, WiznitzerM, YamashitaT

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This double-blind, placebo-controlled study investigated the efficacy and safety of high doses of pyridoxine and magnesium (HDPM) in patients with autism. HDPM was ineffective in ameliorating autistic behaviors and no significant side effects were observed.
Paper Details　
Original Abstract of the Article :
Several reports have described salutary effects such as decreased physical aggression and improved social responsiveness being associated with the administration of high doses of pyridoxine and magnesium (HDPM) in open-labeled and controlled studies of patients with autism. Despite this fact, this i...See full text at original site
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引用元：
https://doi.org/10.1023/a:1025861522935

データ提供：米国国立医学図書館（NLM）

High-Dose Pyridoxine and Magnesium Administration in Children with Autistic Disorder

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that can present a range of challenges. This research investigates the efficacy of high-dose pyridoxine (vitamin B6) and magnesium in children with ASD. The study aimed to determine whether this treatment could improve behavioral symptoms and overall well-being in children with ASD.

Pyridoxine and Magnesium in ASD Treatment: A Double-Blind, Placebo-Controlled Study

This double-blind, placebo-controlled study found that high-dose pyridoxine and magnesium did not have a significant effect on behavioral symptoms in children with ASD. The results suggest that this treatment is unlikely to be a beneficial option for managing ASD.

Challenges in ASD Treatment and Research

ASD research continues to face significant challenges in finding effective treatments. This study highlights the need for continued research to explore other potential interventions for ASD, ultimately aiming to improve the lives of individuals with this complex disorder.

Dr.Camel's Conclusion

Imagine a camel navigating a vast and unpredictable desert, searching for a hidden oasis of relief. This research is like embarking on a quest to find a solution for ASD, but in this case, the oasis remains elusive. The search for effective treatments continues, and we must remain hopeful that new discoveries will emerge on the horizon.

Date :
  1. Date Completed 1997-10-15
  2. Date Revised 2019-09-20
Further Info :

Pubmed ID

9261669

DOI: Digital Object Identifier

10.1023/a:1025861522935

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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