Treatment of children and young adults with early-stage non-Hodgkin's lymphoma.

Author: BerardC W, DonaldsonS S, LinkM P, MurphyS B, ShusterJ J

Paper Details 
Original Abstract of the Article :
BACKGROUND: Children and young adults with early-stage non-Hodgkin's lymphoma have an excellent prognosis, but treatment is prolonged and is associated with many side effects. We performed two studies to determine whether therapy could be simplified. METHODS: Between 1983 and 1991, we conducted two...See full text at original site
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引用元:
https://doi.org/10.1056/NEJM199710303371802

データ提供:米国国立医学図書館(NLM)

Treating Early-Stage Non-Hodgkin's Lymphoma: A Simplified Approach

Non-Hodgkin's lymphoma (NHL) is a complex and challenging disease, like a vast and treacherous desert of medical complexities. This research explores the efficacy of simplified treatment regimens for children and young adults with early-stage NHL, seeking to reduce the duration of therapy and minimize side effects. The study conducted two consecutive trials, comparing different chemotherapy regimens and evaluating their impact on patient outcomes. It's like exploring two different paths through the desert, seeking the most effective route to treatment.

A Simplified Approach to Treatment

The researchers discovered that a nine-week chemotherapy regimen without irradiation was effective for most patients with early-stage, nonlymphoblastic NHL. This finding suggests that a shorter and less intensive treatment approach might be sufficient for certain patient groups.

Minimizing Side Effects and Maintaining Quality of Life

This research highlights the importance of considering the impact of treatment on patient quality of life, striving to minimize side effects and improve overall well-being. It emphasizes the need for ongoing research and tailored treatment approaches to optimize outcomes for children and young adults with NHL.

Dr.Camel's Conclusion

This research presents a more efficient route through the desert of NHL treatment, demonstrating that a simplified approach can be effective for certain patient groups. The study encourages further exploration of individualized treatment strategies, seeking to minimize the burden of therapy and improve the quality of life for patients with this challenging disease.

Date :
  1. Date Completed 1997-11-04
  2. Date Revised 2017-11-16
Further Info :

Pubmed ID

9345074

DOI: Digital Object Identifier

10.1056/NEJM199710303371802

Related Literature

SNS
PICO Info
in preparation
Languages

English

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