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Comparison of respiratory effects of tramadol and oxycodone.

Author: LindgrenL, TarkkilaP, TuominenM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tramadol did not cause respiratory depression in patients undergoing minor surgery under general anesthesia, unlike oxycodone which led to significant respiratory depression.
Paper Details　
Original Abstract of the Article :
STUDY OBJECTIVE: To compare the respiratory effects of tramadol and oxycodone. DESIGN: Placebo-controlled, double-blind randomized study. SETTING: IV Department of Surgery, Helsinki University Central Hospital. PATIENTS: 36 ASA physical status I and II patients undergoing minor surgery with gener...See full text at original site
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引用元：
https://doi.org/10.1016/s0952-8180(97)00147-5

データ提供：米国国立医学図書館（NLM）

Tramadol vs. Oxycodone: A Respiratory Showdown

The use of analgesics is a common practice in medicine, like finding relief from the scorching desert sun. This study investigates the respiratory effects of two commonly used analgesics, tramadol and oxycodone, in patients undergoing minor surgery. The authors, like intrepid explorers, compare the respiratory profiles of these drugs, seeking to identify potential risks.

Respiratory Effects: A Balancing Act

The study found that oxycodone, like a heavy sandstorm, caused significant respiratory depression, while tramadol had a minimal impact on breathing. This highlights the importance of understanding the individual respiratory profiles of different medications, making informed decisions about patient care.

Navigating the Desert of Analgesics: Choosing the Right Path

This research provides valuable insights into the respiratory effects of commonly used analgesics. It emphasizes the importance of choosing the appropriate medication based on the patient's individual needs and risk factors. Just as a wise camel chooses the safest path through the desert, healthcare providers must select analgesics that minimize the risk of adverse effects.

Dr. Camel's Conclusion

This study serves as a reminder that even seemingly safe medications can have significant effects on our bodies. It underscores the importance of understanding the potential risks and benefits of different drugs, ensuring that we make informed decisions about patient care. By carefully navigating the desert of medication options, we can provide the best possible treatment for our patients.

Date :
  1. Date Completed 1997-12-04
  2. Date Revised 2019-09-14
Further Info :

Pubmed ID

9347436

DOI: Digital Object Identifier

10.1016/s0952-8180(97)00147-5

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PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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