A comparison a amitriptyline and maprotiline in the treatment of painful polyneuropathy in diabetics and nondiabetics.

Author: ArnqvistH, BoivieJ, HolmgrenH, LindströmT, ThorellL H, VrethemM

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare amitriptyline and maprotiline in the treatment of painful polyneuropathy in diabetics and nondiabetics. DESIGN: A double-blind, crossover trial of treatment with amitriptyline, maprotiline, and placebo. Treatment was given in randomized order for periods of 4 weeks. Each perio...See full text at original site
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引用元:
https://doi.org/10.1097/00002508-199712000-00009

データ提供:米国国立医学図書館(NLM)

Tackling the Desert of Pain: Amitriptyline vs. Maprotiline for Painful Polyneuropathy

Navigating the vast landscape of pain management, especially in the case of painful polyneuropathy, can be a daunting task. This research, a double-blind crossover trial, delves into the effectiveness of two medications, amitriptyline and maprotiline, in providing relief for patients suffering from this debilitating condition. The authors used a rigorous methodology to evaluate the effectiveness of these medications, comparing their analgesic effects to placebo. The results revealed that amitriptyline emerged as the more effective treatment option, offering a significant reduction in pain intensity compared to maprotiline and placebo. This finding is particularly relevant for those who have been searching for a reliable way to manage the discomfort associated with diabetic and non-diabetic painful polyneuropathy.

Amitriptyline Shows Promise for Painful Polyneuropathy

The study findings indicate that amitriptyline, a tricyclic antidepressant, was significantly more effective than maprotiline and placebo in reducing pain intensity in patients with painful polyneuropathy. The study observed a significant reduction in pain intensity when using amitriptyline, suggesting a more effective pain-relieving effect compared to maprotiline. This discovery, like a refreshing oasis in the desert, offers hope for patients seeking pain relief.

Navigating the Sands of Pain Relief: Amitriptyline for Painful Polyneuropathy

Amitriptyline emerges as a beacon of hope for patients experiencing the relentless pain of polyneuropathy. The study's results suggest that amitriptyline may be a valuable tool for managing pain. However, like navigating the vast and sometimes treacherous desert, it's important to consider the potential side effects of amitriptyline. Always consult your doctor before starting any new medication.

Dr.Camel's Conclusion

This research shines a light on amitriptyline as a potential solution for the painful journey of polyneuropathy. The study's findings suggest that amitriptyline offers a promising avenue for pain management. However, like a seasoned traveler traversing the desert, it's vital to weigh the potential benefits and risks of any treatment option. Always consult with a healthcare professional to determine the best course of action for your individual needs.

Date :
  1. Date Completed 1998-02-10
  2. Date Revised 2019-10-24
Further Info :

Pubmed ID

9430812

DOI: Digital Object Identifier

10.1097/00002508-199712000-00009

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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