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Side effects of adjunct light therapy in patients with major depression.

Author: HatzingerM, HemmeterU, Holsboer-TrachslerE, MüllerM J, SeifritzE

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the side effects of combined trimipramine and bright-light therapy for non-seasonal major depression. The combined therapy had a similar response rate to trimipramine alone but was associated with more sedation, restlessness, and sleep disturbance.
Paper Details　
Original Abstract of the Article :
Adjunct bright-light therapy has been suggested to augment antidepressant drug treatment in patients with non-seasonal major depression. Side effects of the combined therapy have not been investigated thus far. Therefore, somatic complaints and side effects of combined therapy were evaluated in 28 p...See full text at original site
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引用元：
https://doi.org/10.1007/BF02900303

データ提供：米国国立医学図書館（NLM）

The Side Effects of Bright Light Therapy

The field of psychiatry is always searching for new and effective ways to treat mental health conditions. This study explores the side effects of adjunct bright-light therapy in patients with major depression, a condition that can feel like a dark and overwhelming desert. The researchers compared the effects of trimipramine alone to the combination of trimipramine and bright-light therapy, like comparing the effects of a single oasis to the combined benefits of multiple oases.

A Different Side Effect Profile

While both treatment groups had comparable response rates, the study found that adjunct bright-light therapy had a distinct side effect profile compared to trimipramine monotherapy. The most prominent side effects associated with bright-light therapy were aggravated sedation, persisting restlessness, emerging sleep disturbance, decreased appetite, and worsening of vertigo. This information is crucial for clinicians to consider when recommending bright-light therapy, enabling them to better guide their patients through the desert of treatment options.

Navigating the Path to Recovery

This study provides valuable insights into the potential side effects of bright-light therapy, reminding us that every treatment comes with its own set of considerations. By understanding these potential side effects, clinicians can better tailor treatment plans to meet the individual needs of their patients, ensuring that they can navigate the path to recovery with greater confidence and fewer obstacles.

Dr. Camel's Conclusion

This study, like a lantern in the desert, illuminates the potential side effects of bright-light therapy, highlighting the importance of carefully weighing the risks and benefits of different treatment options. By understanding the unique side effect profile of this therapy, clinicians can better guide their patients through the desert of depression, ensuring they find a path to recovery that is both effective and safe. It's a reminder that even in the search for a cure, we must always be mindful of the potential consequences of our actions.

Date :
  1. Date Completed 1998-03-05
  2. Date Revised 2023-03-17
Further Info :

Pubmed ID

9444494

DOI: Digital Object Identifier

10.1007/BF02900303

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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