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Comparative study of budesonide as a nebulized suspension vs pressurized metered-dose inhaler in adult asthmatics.

Author: BisgaardH, MunchE, NikanderK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Nebulized budesonide was found to be as effective as budesonide administered with a spacer in treating adult asthmatics. The nebulized treatment was at least as efficient as the pMDI plus spacer treatment and the apparent order of effect was 4 mg nebulized suspension treatment > or = 1 mg nebulized suspension treatment > or = 0.8 mg pMDI with spacer treatment.
Paper Details　
Original Abstract of the Article :
The study objective was to compare the effect of budesonide administered as a nebulized suspension as compared to a spray with a spacer in adult asthmatics. In a double-blind, double-dummy crossover study, 26 adult patients with moderately severe unstable asthma were randomized to three 4-week treat...See full text at original site
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引用元：
https://doi.org/10.1016/s0954-6111(98)90031-2

データ提供：米国国立医学図書館（NLM）

Budesonide Delivery Systems: A Tale of Two Inhalers

In the realm of respiratory medicine, the search for optimal drug delivery systems is an endless quest. This study delves into the fascinating world of budesonide, a medication commonly used to treat asthma. Researchers compared the efficacy of budesonide administered via a nebulized suspension versus a pressurized metered-dose inhaler (pMDI) with a spacer in adult asthmatics. The results, reminiscent of the shifting sands of a desert, revealed that nebulized budesonide may be as effective as pMDI, especially when synchronized with inspiration. The study’s findings add to the growing body of evidence that proper delivery of medication is just as important as the medication itself.

The Importance of Delivery in Asthma Treatment

This research highlights the importance of choosing the right delivery method for asthma medications. The results suggest that nebulized budesonide, when delivered correctly, might be a viable alternative to traditional inhalers for some patients. This realization is like discovering a hidden oasis in the desert of asthma treatment options, potentially offering a more efficient and effective way for patients to manage their condition.

Inhaling the Future of Asthma Treatment: A Doctor's Perspective

The study emphasizes the need for clinicians to carefully consider the individual needs and preferences of their patients when choosing asthma treatment modalities. This careful approach is akin to navigating the vast desert of treatment options, ensuring that patients receive the care that best suits their unique circumstances. Ultimately, finding the right medication and delivery system for asthma can help patients manage their condition effectively, leading to a smoother journey through the desert of symptoms.

Dr. Camel's Conclusion

This study sheds light on the crucial role of drug delivery in asthma treatment, suggesting that nebulized budesonide might be a valuable alternative for some patients. This research exemplifies the importance of continued exploration of different delivery methods to optimize treatment effectiveness and ultimately improve the lives of those living with asthma.
Date :
  1. Date Completed 1998-04-01
  2. Date Revised 2019-09-05
Further Info :

Pubmed ID

9519224

DOI: Digital Object Identifier

10.1016/s0954-6111(98)90031-2

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・Effects of budesonide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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