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Amoxicillin/metronidazole/omeprazole/clarithromycin: a new, short quadruple therapy for Helicobacter pylori eradication.

Author: AmmonS, KlotzU, SchneiderE, TreiberG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Quadruple therapy regimens for Helicobacter pylori eradication were evaluated, as triple therapy regimens have become the new standard therapy. Triple therapy regimens have success rates of about 90%, but they are still costly, duration is about one week or less, and side-effects are not negligible.
Paper Details　
Original Abstract of the Article :
Triple therapy regimens including two antibiotics plus acid suppression have become the new standard therapy in Helicobacter pylori eradication because of success rates of about 90%. However, these regimens are still costly, duration is about one week or less, and side-effects are not negligible. We...See full text at original site
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引用元：
https://doi.org/10.1046/j.1523-5378.1998.08019.x

データ提供：米国国立医学図書館（NLM）

A New, Short Quadruple Therapy for *Helicobacter pylori* Eradication

This study evaluates a new quadruple therapy regimen for the eradication of *Helicobacter pylori*, a bacterium that can cause gastritis, ulcers, and other digestive problems. The researchers explore the efficacy and safety of a short-duration quadruple therapy consisting of amoxicillin, metronidazole, omeprazole, and clarithromycin. The study aims to find a more efficient and effective treatment option for *Helicobacter pylori* infection.

Efficacy of a Short-Duration Quadruple Therapy

The study found that the new quadruple therapy regimen was highly effective in eradicating *Helicobacter pylori*, achieving an eradication rate of about 90%. This suggests that the short-duration quadruple therapy could be a promising alternative to standard triple therapy regimens. The authors also highlight the potential for reducing treatment costs and side effects with this shorter regimen.

Potential for Improved *Helicobacter pylori* Treatment

The findings of this study provide evidence for a new, efficient, and effective treatment option for *Helicobacter pylori* infection. The short-duration quadruple therapy could potentially improve patient outcomes by reducing treatment costs, minimizing side effects, and reducing the risk of developing antibiotic resistance. It's like discovering a shortcut through the vast desert of *Helicobacter pylori* treatment, offering a more efficient and effective path to eradication.

Dr. Camel's Conclusion

This study explores a new, short-duration quadruple therapy for *Helicobacter pylori* eradication. The findings suggest that this regimen could be a valuable addition to the treatment arsenal for *Helicobacter pylori* infection. It's like finding a hidden oasis in the vast desert of *Helicobacter pylori* treatment, offering a potential solution that is both effective and efficient.

Date :
  1. Date Completed 1998-05-07
  2. Date Revised 2019-11-02
Further Info :

Pubmed ID

9546119

DOI: Digital Object Identifier

10.1046/j.1523-5378.1998.08019.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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