Paper Details

  1. Home
  2. Paper Details

Effects of alcohol, zolpidem, and some other sedatives and hypnotics on human performance and memory.

Author: KalskaH, MattilaM J, SeppäläT, VanakoskiJ

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Zolpidem, a hypnotic drug, impairs cognitive and psychomotor skills more than other hypnotics, including diazepam, oxazepam, and zopiclone. It may have less detrimental effects on memory than diazepam.
Paper Details　
Original Abstract of the Article :
Zolpidem (Zol), an omega1-agonist, acts via GABA(A) receptors but may differ qualitatively from diazepam (Dz) and other benzodiazepines (BZDs). We conducted a placebo-controlled, randomized, double-blind, and crossover study to compare the psychomotor and cognitive effects of 15 mg Zol with those of...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/s0091-3057(97)00506-6

データ提供：米国国立医学図書館（NLM）

The Impact of Sedatives and Hypnotics on Human Performance and Memory

Sedatives and hypnotics are often prescribed to alleviate insomnia and anxiety, but their effects on human performance and cognitive abilities are not always well-understood. This research investigates the impact of different sedatives and hypnotics, including zolpidem, diazepam, oxazepam, zopiclone, and ethanol, on psychomotor and cognitive functions. The study, published in 2000, conducted a placebo-controlled, randomized, double-blind, and crossover study to compare the effects of these substances on human performance and memory.

Zolpidem: A Unique Impact on Cognitive Function

The findings of this research highlight the unique effects of zolpidem on cognitive function. [The study] found that zolpidem impaired coordinative, reactive, and cognitive skills more significantly than other agents, and these impairments persisted for a longer duration. The study also observed that zolpidem, diazepam, and ethanol all tended to impair learning and memory, with zolpidem having the most detrimental effect.

Navigating Sleep Aids: Weighing the Risks and Benefits

This research emphasizes the importance of understanding the potential risks and benefits of different sedatives and hypnotics, particularly their impact on cognitive function. The study's findings highlight the need for caution when using these substances, particularly zolpidem, as they can significantly impair psychomotor and cognitive function.

Dr.Camel's Conclusion

This research is like a camel navigating the desert, encountering a mirage of sedatives and hypnotics. The findings suggest that zolpidem can have a more profound impact on cognitive function than other sedatives, underscoring the need for careful consideration when using these substances.

Date :
  1. Date Completed 1998-06-26
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

9586849

DOI: Digital Object Identifier

10.1016/s0091-3057(97)00506-6

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.