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Comparative efficacy of terfenadine, loratadine, and astemizole in perennial allergic rhinitis.
Author: CrawfordW W, KlaustermeyerW B, LeeP H, PlacikI M
Original Abstract of the Article :
Nonsedating H1 antihistamines such as terfenadine, loratadine, and astemizole are widely prescribed for the treatment of allergic rhinitis. The comparative efficacy of these agents has not been thoroughly studied. We studied 14 subjects in an open-label four-way crossover trial. Patients were recrui...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1177/019459989811800517
データ提供:米国国立医学図書館(NLM)
Nonsedating Antihistamines: Navigating the Allergy Desert with Clarity
Allergies can make life feel like navigating a desert of itchy eyes, runny nose, and sneezing. This research, published in the journal Annals of Allergy, Asthma & Immunology, explores the effectiveness of nonsedating H1 antihistamines, such as terfenadine, loratadine, and astemizole, in alleviating the symptoms of perennial allergic rhinitis.
The authors conducted a four-way crossover trial, comparing the efficacy of these antihistamines to a standard sedating antihistamine, chlorpheniramine. The study found that all four antihistamines provided significant relief from rhinitis symptoms, but there were no significant differences in efficacy between the nonsedating antihistamines.
Nonsedating Antihistamines: A Clear Path Through the Allergy Desert
This research suggests that nonsedating H1 antihistamines offer a clear path through the allergy desert, effectively alleviating symptoms without causing drowsiness. This provides patients with a valuable treatment option that allows them to navigate their daily lives with more clarity and comfort.
Navigating Allergies with Confidence: Choosing the Right Treatment
The desert of allergies can be a challenging landscape, but this research provides valuable insights into the effectiveness of nonsedating antihistamines. By understanding the various treatment options available, patients can choose the most appropriate approach for their needs, enabling them to navigate their allergies with confidence and comfort.
Dr. Camel's Conclusion
Navigating the desert of allergies can be a daunting task, but nonsedating antihistamines offer a clear path to relief. This research provides evidence that these medications can effectively alleviate symptoms without the side effects of drowsiness, allowing patients to navigate their allergies with clarity and confidence.
Date :
- Date Completed 1998-06-02
- Date Revised 2017-02-14
Further Info :
Related Literature
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