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Combined chemo-endocrine adjuvant therapy for patients with operable breast cancer: still a question?

Author: CoatesA, ColleoniM, GoldhirschA, PaganiO

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Treatment after surgery for breast cancer can delay recurrence and improve survival. Combining chemotherapy and hormone therapy appears to be the most effective approach for most, if not all, patients. While chemotherapy has proven beneficial, more research is needed to determine the best combination of drugs, dosage, and timing of treatment. Hormonal therapy, such as tamoxifen, has been particularly useful for patients with hormone receptor-positive tumors. Additional hormonal agents, such as fluoxymesterone acetate, medroxyprogesterone acetate, and LH-RH analogs, are also being studied. Further research is needed to clarify the optimal treatment approach for different groups of patients.
Paper Details　
Original Abstract of the Article :
Adjuvant systemic treatment delays relapse and prolongs survival in patients with operable breast cancer. However, the relative wealth of available agents and the heterogeneity of the target population contribute to considerable uncertainty about the optimal approach to particular patient groups. Sy...See full text at original site
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引用元：
https://doi.org/10.1016/s0305-7372(98)90068-8

データ提供：米国国立医学図書館（NLM）

Adjuvant Therapy for Breast Cancer: Navigating the Shifting Sands of Treatment Options

Breast cancer, like a relentless desert storm, poses a significant challenge for both patients and healthcare professionals. This systematic review delves into the complexities of adjuvant systemic treatment for operable breast cancer, examining the effectiveness of various treatment approaches. The researchers, like skilled navigators charting a course through the desert, evaluate the benefits and challenges of different adjuvant therapies.

A Multifaceted Approach: The Value of Combined Chemo-Endocrine Therapy

The review suggests that combined chemo-endocrine therapy, like a caravan equipped with multiple resources for survival, might be the most effective approach for many breast cancer patients. This multipronged strategy, combining chemotherapy and endocrine therapy, holds promise for improving patient outcomes and prolonging survival.

A Desert Oasis of Hope: Seeking Optimal Treatment for Breast Cancer

This research, like a beacon of hope in the vast desert of breast cancer treatment, underscores the importance of personalized medicine. The authors emphasize the need for tailored treatment plans, considering individual patient characteristics and tumor biology, to maximize the effectiveness of adjuvant therapy.

Dr. Camel's Conclusion

This review, like a well-traveled caravan route through the desert, offers valuable insights into the evolving landscape of breast cancer treatment. It highlights the potential of combined chemo-endocrine therapy and the need for personalized treatment approaches to optimize patient outcomes.
Date :
  1. Date Completed 1998-06-11
  2. Date Revised 2019-10-24
Further Info :

Pubmed ID

9606365

DOI: Digital Object Identifier

10.1016/s0305-7372(98)90068-8

SNS
PICO Info
in preparation
Languages

English

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