Alpha-blockade therapy for benign prostatic hyperplasia: from a nonselective to a more selective alpha1A-adrenergic antagonist.

Author: BeduschiM C, BeduschiR, OesterlingJ E

Paper Details 
Original Abstract of the Article :
Benign prostatic hyperplasia (BPH) is very common in older men, causing symptoms that can markedly impair quality of life. Surgical treatment, typically transurethral resection of the prostate (TURP), is highly effective but can be costly and is associated with the risk for significant morbidity. Me...See full text at original site
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引用元:
https://doi.org/10.1016/s0090-4295(98)00140-x

データ提供:米国国立医学図書館(NLM)

Alpha-blockade Therapy: A Journey Towards Prostate Health

Benign prostatic hyperplasia (BPH), a common condition affecting older men, can significantly impact their quality of life. Imagine a camel struggling to navigate a narrow desert passageway – that's what BPH can feel like for men.

This study focuses on the evolution of alpha-blockade therapy in managing BPH, exploring the shift from nonselective alpha-antagonists to more targeted alpha1A-adrenergic antagonists. It's like refining the tools used to clear a desert path, ensuring a smoother journey.

The research highlights the effectiveness of tamsulosin, an alpha1A-adrenergic antagonist, in improving symptoms associated with BPH. This agent, like a skilled desert navigator, targets specific areas of the prostate to alleviate obstruction and improve urinary flow. The study's key findings include [key findings], emphasizing tamsulosin's potential to improve BPH symptoms.

Navigating the Prostate Desert

The study offers promising results for men with BPH, suggesting that tamsulosin can effectively alleviate symptoms. This targeted therapy, like a well-marked path, can help men navigate the prostate desert and reclaim their quality of life.

A New Oasis for Prostate Health

The development of more selective alpha1A-adrenergic antagonists, such as tamsulosin, represents a significant advancement in BPH management. This targeted approach, like discovering a new oasis in the desert, offers a more effective and well-tolerated treatment option for men with BPH.

Dr. Camel's Conclusion

This research reminds us that advancements in medical science are constantly evolving, just like the ever-changing landscape of a desert. By understanding the mechanisms of BPH and developing more targeted therapies, we're taking steps toward improving the health and well-being of men worldwide.

Date :
  1. Date Completed 1998-06-19
  2. Date Revised 2019-07-14
Further Info :

Pubmed ID

9609620

DOI: Digital Object Identifier

10.1016/s0090-4295(98)00140-x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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