[Gastroprotection in cancer patients: rational approach, pharmacologic role of antisecretory agents and eventual ulterior prospectives in oncology].

Author: CeccheriniR, MustacchiG

Paper Details 
Original Abstract of the Article :
In view of the large number of cancer patients treated with FANS and/or corticosteroids for long periods of time. Authors discuss how the use of antisecretory drugs for gastroprotection has become common practice in spite of the lack of clear scientific evidence. The paper analyses the principal mec...See full text at original site
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引用元:
https://doi.org/10.1177/03008916980841s104

データ提供:米国国立医学図書館(NLM)

Gastroprotection in Cancer Patients: A Critical Look at Antisecretory Agents

Imagine a camel caravan crossing a vast and unforgiving desert, its members susceptible to the harsh conditions. This study delves into the realm of gastroprotection in cancer patients, exploring the challenges of managing gastrotoxicity associated with cancer treatments. The researchers discuss the use of antisecretory agents, specifically ranitidine and misoprostole, for preventing gastrointestinal complications in cancer patients.

The Importance of Gastroprotection in Cancer Treatment

The study underscores the importance of gastroprotection in cancer patients, emphasizing the risk of gastrotoxicity associated with certain cancer treatments. It's like ensuring the caravan's camels have access to water and food to prevent dehydration and exhaustion. The researchers highlight the need for effective strategies to protect the gastrointestinal tract from damage caused by cancer therapies.

Evaluating the Efficacy of Antisecretory Agents

The study compares the efficacy of ranitidine and misoprostole in preventing gastrointestinal complications in cancer patients. This is like comparing different types of camels for their ability to withstand the harsh desert environment. The researchers found that misoprostole provided significant protection against both gastric and duodenal ulcers, while ranitidine only protected against localized duodenal ulcers. These findings could guide clinicians in selecting the most effective antisecretory agent for their patients.

Dr.Camel's Conclusion

This study emphasizes the need for comprehensive care for cancer patients, particularly those receiving treatments that carry the risk of gastrotoxicity. It's a reminder that supporting the overall health of the patient is vital, just as ensuring the well-being of the camels is crucial for the success of a desert caravan journey. The research highlights the importance of evidence-based decision-making in selecting the most appropriate gastroprotective agent for each patient.

Date :
  1. Date Completed 1998-06-18
  2. Date Revised 2022-10-07
Further Info :

Pubmed ID

9617379

DOI: Digital Object Identifier

10.1177/03008916980841s104

Related Literature

SNS
PICO Info
in preparation
Languages

Italian

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