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Tramadol hydrochloride: analgesic efficacy compared with codeine, aspirin with codeine, and placebo after dental extraction.

Author: BakosL, CroutR J, GravesR W, JacksonD L, MooreP A, SchneiderL G

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tramadol, a novel analgesic with both opioid and aminergic mechanisms of action, was found to be effective in relieving pain following third molar extraction. Tramadol 100 mg was statistically superior to placebo, while tramadol 50 mg was only statistically superior for time of remedication. Gastrointestinal side effects were more common with tramadol than with placebo.
Paper Details　
Original Abstract of the Article :
Tramadol hydrochloride is a novel, centrally acting analgesic with two complementary mechanisms of action: opioid and aminergic. Relative to codeine, tramadol has similar analgesic properties but may have fewer constipating, euphoric, and respiratory depressant effects. A two-center randomized doubl...See full text at original site
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引用元：
https://doi.org/10.1002/j.1552-4604.1998.tb05794.x

データ提供：米国国立医学図書館（NLM）

Tramadol Hydrochloride: A New Oasis in the Desert of Dental Pain

This double-blind randomized controlled trial evaluates the analgesic efficacy of [tramadol hydrochloride] compared to other pain relievers for [dental extraction pain]. The authors found that tramadol 100 mg and 50 mg, along with aspirin with codeine, provided statistically significant pain relief compared to placebo. Tramadol was found to be comparable to aspirin with codeine in terms of overall pain relief, but with potentially fewer gastrointestinal side effects. The study highlights the potential benefits of tramadol as a pain management option for dental procedures.

Navigating the Painscape: Finding the Right Relief

The findings of this study provide valuable insights into the effectiveness of tramadol for dental pain. The comparison with other analgesics reveals that tramadol can provide similar pain relief with potentially fewer side effects. This information is valuable for dentists and patients seeking effective and tolerable pain management options for dental procedures. It's like having a map to navigate the often challenging terrain of pain management, guiding you towards the most effective and comfortable route.

Dental Pain Management: A Dr.Camel Perspective

Dental procedures can be a source of anxiety for many people, and effective pain management is essential for a positive experience. This research provides valuable information about the efficacy and safety of tramadol for dental pain relief. As Dr. Camel, I encourage patients to discuss their pain management options with their dentists to find the best approach for their individual needs. It's like choosing the right camel for a long journey - finding the right analgesic can make all the difference!

Dr.Camel's Conclusion

This research demonstrates the analgesic efficacy of tramadol hydrochloride for dental extraction pain, suggesting it is a viable option for managing this type of pain with potentially fewer gastrointestinal side effects.

Date :
  1. Date Completed 1998-09-25
  2. Date Revised 2020-12-09
Further Info :

Pubmed ID

9650546

DOI: Digital Object Identifier

10.1002/j.1552-4604.1998.tb05794.x

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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