Paper Details

  1. Home
  2. Paper Details

One-year follow-up of young children hospitalized for wheezing: the influence of early anti-inflammatory therapy and risk factors for subsequent wheezing and asthma.

Author: KorppiM, ReijonenT M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Early anti-inflammatory therapy with budesonide or cromolyn sodium did not significantly decrease the incidence of asthma in children hospitalized for wheezing. Several risk factors for asthma were identified, including age over 12 months at the time of the initial wheezing episode, lack of a viral cause for wheezing, history of wheezing, atopy, family history of atopy, and elevated serum eosinophil cationic protein.
Paper Details　
Original Abstract of the Article :
We investigated the 1-year outcome of children hospitalized for wheezing, paying special attention to the effect of early anti-inflammatory therapy. In addition, we identified risk factors for recurrent wheezing and asthma. Eighty-eight children under 2 years old treated in the hospital for wheezing...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/(sici)1099-0496(199808)26:2<113::aid-ppul7>3.0.co;2-n

データ提供：米国国立医学図書館（NLM）

Wheezing in Young Children: A One-Year Follow-Up

This study investigates the long-term outcomes of young children hospitalized for wheezing, with a focus on the impact of early anti-inflammatory therapy. The researchers analyzed data from 88 children under 2 years old, following their health for one year. They aimed to identify risk factors for recurrent wheezing and asthma and determine the effectiveness of early anti-inflammatory treatment.

Early Anti-Inflammatory Therapy: Limited Impact on Asthma

The study found that early anti-inflammatory therapy for four months did not significantly reduce the occurrence of asthma in children hospitalized for wheezing. The researchers identified several risk factors for asthma, including age over 12 months at the time of the initial wheezing episode, a history of wheezing, atopy, and elevated serum eosinophil cationic protein (ECP) levels.

Asthma in Children: A Complex Challenge

This study offers valuable insights into the long-term outcomes of wheezing in young children. The limited impact of early anti-inflammatory therapy highlights the complexity of asthma development. It's like navigating a vast desert landscape, where multiple factors contribute to the formation of sand dunes, requiring us to adopt a multifaceted approach for prevention and management.

Dr.Camel's Conclusion

This research underscores the need for a comprehensive understanding of the factors contributing to asthma development in young children. While early anti-inflammatory therapy may not always prevent asthma, identifying and managing risk factors such as age, history of wheezing, and atopy can play a crucial role in reducing asthma risk.
Date :
  1. Date Completed 1998-11-20
  2. Date Revised 2019-09-15
Further Info :

Pubmed ID

9727762

DOI: Digital Object Identifier

10.1002/(sici)1099-0496(199808)26:2<113::aid-ppul7>3.0.co;2-n

Related Literature

Article Analysis
・Effects of cromolyn oral inhalation
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.